PANK2 Antibodies

AND PANK2 ELISA kits, PANK2 Proteins

Many biological assays use antibodies to detect PANK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PANK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PANK2 antibodies...

We validate the specificity of these antibodies to PANK2 by testing them on tissues known to express PANK2 positively and negatively. Browse below to find the PANK2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PANK2 Infographic by Boster Bio

All PANK2 Products

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Applications

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Anti-PANK2 Antibody

Western blot (WB) analysis of PANK2 polyclonal antibody at 1:500 dilution
Lane1:MCF-7 cell lysate
Lane2:sp2/0 cell lysate
Lane3:PC12 cell lysate

Human, Mouse, Rat

$405
Cat # A02776-1
100ul

Anti-PANK2 Mouse Monoclonal Antibody [Clone ID: OTI3H9]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PANK2 (Right lane) cDNA for 48 hrs and lysed

Figure from citation: Western Blot of PANK2 protein level by using anti-PANK2 antibody in different mitochondrial compartments isolated from WT mouse brain and WT mouse fibroblasts

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PANK2 monoclonal antibody

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M02776
100 µl

PANK2 (NM_153638) Human Over-expression Lysate

PANK2 Human Over-expression Lysates NM_024960

Human

$960
Cat # LS080025
20 µg, 100 µg

Anti-PANK2 Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A02776-2
100 μl/vial

PANK2 Overview

Facts about Pantothenate kinase 2, mitochondrial.

PANK2 3D structure. Source: alphafold

Pantothenate kinase 2, mitochondrial (PANK2)

May be the master regulator of the CoA biosynthesis. .

Gene Information

Human
Gene Name:	PANK2
Uniprot:	Q9BZ23
Entrez:	80025

Family

Belongs to:

type II pantothenate kinase family

Alternative Names

C20orf48; EC 2.7.1.33; FLJ17232; Hallervorden-Spatz syndrome; HARPFLJ11729; hPanK2; HSS; MGC15053; NBIA1; pantothenate kinase 2; pantothenate kinase 2, mitochondrial; Pantothenic acid kinase 2; PKANneurodegeneration with brain iron accumulation 1 (Hallervorden-Spatz syndrome)

Molecular Weight

Mass (kDA):
62.681 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (3888781..3933087)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

[Isoform 1]: Mitochondrion.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.

Diseases

Nerve Degeneration
Hallervorden-spatz Syndrome
Neurodegenerative Disorders
Dystonia Disorders
Globus Hystericus
Secondary Parkinson Disease
Dysarthria
Movement Disorders
Dementia
Retinitis Pigmentosa
Neuroaxonal Dystrophies
Iron Metabolism Disorders

Parkinson Disease
Dystrophy
Atrophy
Impaired Cognition
Ataxia
Infantile Neuroaxonal Dystrophy

Pathways

Pathogenesis
Localization
Transport
Lipid Homeostasis
Cognition
Cell Proliferation
Response To Stimulus
G2 Phase
Mitosis
Ion Transport
Gluconeogenesis
Bile Acid Conjugation

Conjugation
Reflex
Cellular Localization
Cell Cycle
Cell Growth
Interphase
Fatty Acid Oxidation

PTMs

Phosphorylation

Oxidation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PANK2

References

PMID: 12554685 by Hoertnagel K., et al. An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria.

PMID: 11479594 by Zhou B., et al. A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.