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- Table of Contents
PCBP1 Antibodies
AND PCBP1 ELISA kits, PCBP1 Proteins
Many biological assays use antibodies to detect PCBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCBP1 antibodies...
Designing a Western blot for PCBP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PCBP1 Western Blot GuideDesigning an IHC experiment for PCBP1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PCBP1 IHC GuidePCBP1 Infographic by Boster Bio
All PCBP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A02636-1
100 μg/vial
Cat # A02636-1
100 μg/vial
PCBP1 Overview
Facts about Poly(rC)-binding protein 1.
Poly(rC)-binding protein 1 (PCBP1)
Single-stranded nucleic acid binding protein which binds preferentially to oligo dC. In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD (PubMed:12414943).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PCBP1 |
| Uniprot: | Q15365 |
| Entrez: | 5093 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
alpha-CP1; Heterogeneous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein X; hnRNP E1; hnRNP-E1; hnRNP-X; HNRPE1; HNRPX; nucleic acid binding protein sub 2.3; Nucleic acid-binding protein SUB2.3; poly(rC) binding protein 1; poly(rC)-binding protein 1
Molecular Weight
Mass (kDA):
37.498 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p13.3 |
| Sequence: | 2; NC_000002.12 (70087477..70089203) |
Tissue Specificity
Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.
Subcellular Localizations
Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Neuroblastoma
- Folic Acid Deficiency
- Liver Neoplasms
- Hypoxia
- Liver Carcinoma
- Malignant Paraganglionic Neoplasm
- Tissue Adhesions
- Leukemia
- Immunologic Deficiency Syndromes
- Adenocarcinoma
Interacting Proteins
- PAK1
- PCBP2
- PPIG
- PRPF8
- PTBP1
- PUF60
- QKI
- RBM39
- SNRPA
- THAP11
Pathways
- Translation
- Mrna Stabilization
- Localization
- Cell Adhesion
- Cell Migration
- Cell Cycle
- Cell Proliferation
- Cell Growth
- Rna Interference
- Transport
- Virion Assembly
- Gene Silencing
- Aging
PTMs
- Phosphorylation
- Cleavage
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCBP1
bosterbio.com/bosterbio-gene-info-cards/PCBP1
References
PMID: 7607214 by Leffers H., et al. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains.
PMID: 7556077 by Kiledjian M., et al. Identification of two KH domain proteins in the alpha-globin mRNP stability complex.