PCID2 Antibodies

AND PCID2 ELISA kits, PCID2 Proteins

Many biological assays use antibodies to detect PCID2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCID2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCID2 antibodies...

We validate the specificity of these antibodies to PCID2 by testing them on tissues known to express PCID2 positively and negatively. Browse below to find the PCID2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PCID2 Infographic by Boster Bio

All PCID2 Products

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Human PCID2 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTQ5JVF3
Starting from 20ug

PCID2 Overview

Facts about PCI domain-containing protein 2.

PCID2 3D structure. Source: alphafold

PCI domain-containing protein 2 (PCID2)

Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Part of the TREX-2 complex (transcription and export complex 2), composed of ENY2, GANP, PCID2, SEM1, and either centrin CETN2 or CETN3 (PubMed:22307388).

The TREX-2 complex functions in docking export- competent ribonucleoprotein particles (mRNPs) into the atomic entrance of the nuclear pore complex (atomic basket). TREX-2 participates in mRNA export and accurate chromatin placement in the nucleus by tethering genes to the nuclear periphery.

Gene Information

Human
Gene Name:	PCID2
Uniprot:	Q5JVF3
Entrez:	55795

Family

Belongs to:

CSN12 family

Alternative Names

CSN12-like protein; DKFZp686C20226; F10; FLJ11305; FLJ99362; MGC16774; PCI domain containing 2; PCI domain-containing protein 2

Molecular Weight

Mass (kDA):
46.03 kDA

Genomic Context


Human

Location:	13q34
Sequence:	13; NC_000013.11 (113165002..113209467, complement)

Subcellular Localizations

Cytoplasm. Nucleus, nuclear pore complex.

Diseases

Polyploidy

Interacting Proteins

IKZF3
SEM1

Pathways

Cell Differentiation
Mrna Processing
B Cell Differentiation
Nuclear Export

PTMs

Acetylation

Phosphoprotein

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCID2

References

PMID: 22307388 by Jani D., et al. Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export.

PMID: 23591820 by Umlauf D., et al. The human TREX-2 complex is stably associated with the nuclear pore basket.