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- Table of Contents
PDE6B Antibodies
AND PDE6B ELISA kits, PDE6B Proteins
Many biological assays use antibodies to detect PDE6B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDE6B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDE6B antibodies...
Designing a Western blot for PDE6B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PDE6B Western Blot GuidePDE6B Infographic by Boster Bio
All PDE6B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02659-1
100 μg/vial
Cat # A02659-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02659-1
100 μg/vial
Cat # M02659-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02659
100 μg/vial
Cat # M02659
100 μg/vial
PDE6B Overview
Facts about Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta.
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B)
This protein participates in processes of transmission and amplification of the visual signal. Needed for the formation of a functional phosphodiesterase holoenzyme.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PDE6B |
| Uniprot: | P35913 |
| Entrez: | 5158 |
Family
| Belongs to: |
|---|
| cyclic nucleotide phosphodiesterase family |
Alternative Names
CSNB3; EC 3.1.4; EC 3.1.4.35; GMP-PDE beta; PDEBrod cGMP-phosphodiesterase beta-subunit; phosphodiesterase 6B, cGMP-specific, rod, beta; rd1; rod cGMP-specific 3'-5'-cyclic phosphodiesterase subunit beta; RP40CSNBAD2
Molecular Weight
Mass (kDA):
98.336 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4p16.3 |
| Sequence: | 4; NC_000004.12 (587325..670892) |
Subcellular Localizations
Membrane; Lipid-anchor.
Diseases
- Retinal Degeneration
- Retinitis Pigmentosa
- Blind Vision
- Retinal Diseases
- Night Blindness
- Atrophy
- Dog Diseases
- Atrophic Retina
- Retinoblastoma
- Congenital Stationary Night Blindness
- Abnormal Degeneration
Pathways
- Phototransduction
- Localization
- Cell Death
- Pathogenesis
- Transport
- Reflex
- Cell Division
- Synaptic Transmission
- Ovulation
- Habituation
- Aging
- Proteolysis
- Neurogenesis
PTMs
- Phosphorylation
- Prenylation
- Farnesylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDE6B
bosterbio.com/bosterbio-gene-info-cards/PDE6B
References
PMID: 1720239 by Weber B., et al. Genomic organization and complete sequence of the human gene encoding the beta-subunit of the cGMP phosphodiesterase and its localisation to 4p16.3.
PMID: 1338685 by Khramtsov N.V., et al. Structural studies of cDNA and the gene for the beta-subunit of cGMP phosphodiesterase from human retina.