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- Table of Contents
PDHA1 Antibodies
AND PDHA1 ELISA kits, PDHA1 Proteins
Many biological assays use antibodies to detect PDHA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDHA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDHA1 antibodies...
Designing a Western blot for PDHA1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PDHA1 Western Blot GuideDesigning an IHC experiment for PDHA1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PDHA1 IHC GuidePDHA1 Infographic by Boster Bio
All PDHA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01906
100 μl
Cat # M01906
100 μl
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # P01906
100 μl/vial
Cat # P01906
100 μl/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, ICC, WB
$370
Cat # A01906-4
100 μl/vial
Cat # A01906-4
100 μl/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01906-2
20μL, 40μL, 100μL, 200μL
Cat # M01906-2
20μL, 40μL, 100μL, 200μL
PDHA1 Overview
Facts about Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial.
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1)
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PDHA1 |
| Uniprot: | P08559 |
| Entrez: | 5160 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
EC 1.2.4.1; PDHA; PDHE1-A type I; PHE1APDHCE1A; pyruvate dehydrogenase (lipoamide) alpha 1; pyruvate dehydrogenase complex, E1-alpha polypeptide 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Molecular Weight
Mass (kDA):
43.296 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp22.12 |
| Sequence: | X; NC_000023.11 (19343893..19361718) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Mitochondrion matrix.
Diseases
- Pyruvate Dehydrogenase Complex Deficiency Disease
- Acidosis
- Acidosis, Lactic
- Ataxia
- Muscle Hypotonia
- Leigh Disease
- Congenital Absence
- Embryonic Mosaic
- Mitochondrial Diseases
- Lactic Acidemia
- Dystonia Disorders
Interacting Proteins
- IMMT
- PDHB
- PDK1
Pathways
- Localization
- Brain Development
- Oxidative Phosphorylation
- Spermatogenesis
- Translation
- Pathogenesis
- Glycolysis
- Transport
- Pyruvate Oxidation
- Tricarboxylic Acid Cycle
- Dna Methylation
PTMs
- Decarboxylation
- Phosphorylation
- Demethylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDHA1
bosterbio.com/bosterbio-gene-info-cards/PDHA1
References
PMID: 2227443 by Koike K., et al. Characterization and nucleotide sequence of the gene encoding the human pyruvate dehydrogenase alpha-subunit.
PMID: 2748588 by Ho L., et al. Characterization of cDNAs encoding human pyruvate dehydrogenase alpha subunit.