PDE6C Antibodies

AND PDE6C ELISA kits, PDE6C Proteins

Many biological assays use antibodies to detect PDE6C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDE6C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDE6C antibodies...

We validate the specificity of these antibodies to PDE6C by testing them on tissues known to express PDE6C positively and negatively. Browse below to find the PDE6C antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDE6C Infographic by Boster Bio

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PDE6C (NM_006204) Human Over-expression Lysate

Human

$960
Cat # LS005146
20 µg, 100 µg

PDE6C Overview

Facts about Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'.

PDE6C 3D structure. Source: alphafold

Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (PDE6C)

As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP. .

Gene Information

Human
Gene Name:	PDE6C
Uniprot:	P51160
Entrez:	5146

Family

Belongs to:

cyclic nucleotide phosphodiesterase family

Alternative Names

Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

Molecular Weight

Mass (kDA):
99.147 kDA

Genomic Context


Human

Location:	10q23.33
Sequence:	10; NC_000010.11 (93612537..93666010)

Subcellular Localizations

Cell membrane; Lipid-anchor; Cytoplasmic side.

Diseases

Cone dystrophy 4 (COD4)

PTMs

Lipoprotein

Methylation

Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDE6C

References

PMID: 8543163 by Viczian A.S., et al. Isolation and characterization of a cDNA encoding the alpha' subunit of human cone cGMP-phosphodiesterase.

PMID: 7490077 by Piriev N.I., et al. Gene structure and amino acid sequence of the human cone photoreceptor cGMP-phosphodiesterase alpha' subunit (PDEA2) and its chromosomal localization to 10q24.