PDS5B Antibodies

AND PDS5B ELISA kits, PDS5B Proteins

Many biological assays use antibodies to detect PDS5B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDS5B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDS5B antibodies...

We validate the specificity of these antibodies to PDS5B by testing them on tissues known to express PDS5B positively and negatively. Browse below to find the PDS5B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDS5B Infographic by Boster Bio

All PDS5B Products

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Anti-PDS5B Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04823
100ul

Anti-PDS5B Antibody Picoband®

Western blot analysis of PDS5B using anti-PDS5B antibody (A04823-1)

Flow Cytometry analysis of PC-3 cells using anti-PDS5B antibody (A04823-1)

Human, Mouse

ELISA, Flow Cytometry, WB

$370
Cat # A04823-1
100 µg/vial

PDS5B Overview

Facts about Sister chromatid cohesion protein PDS5 homolog B.

PDS5B 3D structure. Source: alphafold

Sister chromatid cohesion protein PDS5 homolog B (PDS5B)

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis into DNA replication.

Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays a significant role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

Gene Information

Human
Gene Name:	PDS5B
Uniprot:	Q9NTI5
Entrez:	23047

Family

Belongs to:

PDS5 family

Alternative Names

Androgen-induced proliferation inhibitorKIAA0979androgen induced inhibitor of proliferation; Androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; AS3APRIN; CG008; FLJ23236; PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae); sister chromatid cohesion protein PDS5 homolog B

Molecular Weight

Mass (kDA):
164.667 kDA

Genomic Context


Human

Location:	13q13.1
Sequence:	13; NC_000013.11 (32586432..32778019)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Carcinoma
Prostatic Neoplasms
Neoplasms
Autoimmune Diseases
Malignant Neoplasm Of Breast
Lupus Erythematosus, Systemic
Esophageal Neoplasms
Congenital Abnormality
Cleft Palate
Squamous Cell Carcinoma Of Esophagus
Growth Arrest

Cornelia De Lange Syndrome
Congenital Heart Defects
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Autoimmune Reaction
Autoimmunity
Sclerosis

Interacting Proteins

BRCA2
RAD21
SMC3
STAG1
STAG2

WAPL

Pathways

Sister Chromatid Cohesion
Cell Proliferation
Localization
Cell Cycle
Interphase
Mitosis
Germinal Center Formation
Cell Activation
Stem Cell Differentiation
B Cell Activation
Chromosome Segregation
Cell Cycle Arrest
Anaphase

Cell Division
Asymmetric Cell Division
Prophase
Cell Differentiation
Chromosome Condensation
Meiosis
Mitotic Prophase

PTMs

Glycosylation

Research Areas

Apoptosis
Cell Cycle and Replication
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDS5B

References

PMID: 9459187 by Geck P., et al. Expression of novel genes linked to the androgen-induced, proliferative shutoff in prostate cancer cells.

PMID: 10215036 by Geck P., et al. Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus.