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- Table of Contents
PEBP1 Antibodies
AND PEBP1 ELISA kits, PEBP1 Proteins
Many biological assays use antibodies to detect PEBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PEBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PEBP1 antibodies...
Designing a Western blot for PEBP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PEBP1 Western Blot GuideDesigning an IHC experiment for PEBP1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PEBP1 IHC GuidePEBP1 Infographic by Boster Bio
All PEBP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IHC, WB
$370
Cat # A01668
100 μg/vial
Cat # A01668
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01672-2
100 μg/vial
Cat # A01672-2
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M01668
100 μl
Cat # M01668
100 μl
PEBP1 Overview
Facts about Phosphatidylethanolamine-binding protein 1.
Phosphatidylethanolamine-binding protein 1 (PEBP1)
Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine.
Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
Gene Information
| Human | |
|---|---|
| Gene Name: | PEBP1 |
| Uniprot: | P30086 |
| Entrez: | 5037 |
Family
| Belongs to: |
|---|
| phosphatidylethanolamine-binding protein family |
Alternative Names
HCNP; HCNPpp; hippocampal cholinergic neurostimulating peptide; Neuropolypeptide h3; PBP; PBPPEBP-1; PEBP1; PEBP-1; PEBPHCNPpp; phosphatidylethanolamine binding protein 1; phosphatidylethanolamine-binding protein 1; prostatic binding protein; Prostatic-binding protein; Raf kinase inhibitory protein; RKIP; RKIPRaf kinase inhibitor protein
Molecular Weight
Mass (kDA):
21.057 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.23 |
| Sequence: | 12; NC_000012.12 (118136124..118145584) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Cell Invasion
- Carcinoma
- Malignant Neoplasm Of Prostate
- Malignant Neoplasm Of Breast
- Neoplasm Invasiveness
- Mammary Neoplasms
- Prostatic Neoplasms
- Melanoma
- Adenocarcinoma
- Tumor Progression
Interacting Proteins
- ALOX15
- RAF1
- TNFRSF19
- Tnfrsf19
Pathways
- Cell Proliferation
- Pathogenesis
- Cell Migration
- Cell Cycle
- Localization
- Secretion
- Cell Differentiation
- Epithelial To Mesenchymal Transition
- Sensitization
- Reverse Transcription
- Methylation
- Cell Growth
- Angiogenesis
PTMs
- Phosphorylation
Research Areas
- Cancer
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PEBP1
bosterbio.com/bosterbio-gene-info-cards/PEBP1
References
PMID: 8144042 by Hori N., et al. A human cDNA sequence homologue of bovine phosphatidylethanolamine- binding protein.
PMID: 7637590 by Tohdoh N., et al. Sequence homology of rat and human HCNP precursor proteins, bovine phosphatidylethanolamine-binding protein and rat 23-kDa protein associated with the opioid-binding protein.