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Protein pelota homolog Antibodies
AND PELO ELISA kits, Protein pelota homolog Proteins
Many biological assays use antibodies to detect Protein pelota homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein pelota homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein pelota homolog antibodies...
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PELO Overview
Facts about Protein pelota homolog.
Protein pelota homolog (PELO)
Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to discharge non-functional ribosomes and degrade damaged mRNAs.
May have ribonuclease activity (Potential). .
Gene Information
| Human | |
|---|---|
| Gene Name: | PELO |
| Uniprot: | Q9BRX2 |
| Entrez: | 53918 |
Family
| Belongs to: |
|---|
| eukaryotic release factor 1 family |
Alternative Names
EC 3.1; pelota (Drosophila) homolog; pelota homolog (Drosophila); PRO1770; protein pelota homolog
Molecular Weight
Mass (kDA):
43.359 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q11.2 |
| Sequence: | 5; NC_000005.10 (52787916..52804044) |
Tissue Specificity
Ubiquitously expressed.
Subcellular Localizations
Nucleus. Cytoplasm.
Diseases
- Acquired Immunodeficiency Syndrome
- Spermatogenesis Arrest
- Sterility
- Immunologic Deficiency Syndromes
- Neoplasms
- Hiv Infections
- Leukemogenesis
- Malnutrition
- Feeling Despair
- Childhood Acute Myeloid Leukemia
- Sleep Disorders, Circadian Rhythm
- Hematopoietic Neoplasms
Interacting Proteins
- EIF3G
- HAX1
- SRPX
Pathways
- Cell Cycle
- Cell Proliferation
- Translation
- Gastrulation
- Macromolecule Biosynthetic Process
- Male Meiosis
- Sporulation
- Megakaryocyte Differentiation
- Localization
- Biosynthetic Process
- Spermatogenesis
- Methylation
- Tissue Development
PTMs
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PELO
bosterbio.com/bosterbio-gene-info-cards/PELO
References
PMID: 11060452 by Shamsadin R., et al. Molecular cloning, expression and chromosome location of the human pelota gene PELO.