PEX5 Antibodies

AND PEX5 ELISA kits, PEX5 Proteins

Many biological assays use antibodies to detect PEX5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PEX5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PEX5 antibodies...

We validate the specificity of these antibodies to PEX5 by testing them on tissues known to express PEX5 positively and negatively. Browse below to find the PEX5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PEX5 Infographic by Boster Bio

All PEX5 Products

Product

Figures

Specificity

Applications

Price

Anti-Peroxin 5 PEX5 Antibody

6 Q&As

Human, Mouse

$399
Cat # A02406-1
100μl

Anti-PEX5 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02406
100ul

Anti-PEX5 Mouse Monoclonal Antibody [Clone ID: OTI6E9]

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M02406
100 µl

PEX5 Overview

Facts about Peroxisomal targeting signal 1 receptor.

PEX5 3D structure. Source: alphafold

Peroxisomal targeting signal 1 receptor (PEX5)

Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. .

Gene Information

Human
Gene Name:	PEX5
Uniprot:	P50542
Entrez:	5830

Family

Belongs to:

peroxisomal targeting signal receptor family

Alternative Names

FLJ50634; FLJ50721; Peroxin-5; peroxisomal biogenesis factor 5; Peroxisomal C-terminal targeting signal import receptor; peroxisomal targeting signal 1 receptor; peroxisomal targeting signal import receptor; peroxisomal targeting signal receptor 1; Peroxisome receptor 1peroxin-5; PTS1 receptor; PTS1-BP; PTS1RFLJ51948; PXR1peroxisomal targeting signal 1 (SKL type) receptor

Molecular Weight

Mass (kDA):
70.865 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (7188653..7218574)

Tissue Specificity

Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13).

Diseases

Zellweger Syndrome
Peroxisomal Disorders
Disorders Of Peroxisome Biogenesis
Aortic Aneurysm, Abdominal
Chondrodysplasia Punctata
Malnutrition
Chondrodysplasia Punctata, Rhizomelic
Muscle Hypotonia
Adrenoleukodystrophy, Neonatal
Adrenoleukodystrophy
Fetal Growth Retardation
Carcinoma

Neoplasms
Dwarfism
Hereditary Diseases
Congenital Abnormality
Infantile Refsum Disease (disorder)
Hypokinesia

Interacting Proteins

ACOT8
AGXT
CAPRIN2
CCDC14
GDPD5

LDHB
PEX12
PEX14
PRR13
S100A6

SQSTM1
TINF2
ZNF772

Pathways

Protein Import
Localization
Transport
Fatty Acid Beta-oxidation
Photorespiration
Rna Interference
Germination
Pathogenesis
Secretion
Receptor Recycling
Protein Transport
Glycolysis
Glyoxylate Cycle

Virulence
Cell Cycle
Meiosis
Developmental Process
Protein Targeting
Gluconeogenesis
Myelination

PTMs

Oxidation
Ubiquitination

Phosphorylation
Reduction

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PEX5

References

PMID: 7719337 by Dodt G., et al. Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders.

PMID: 7790377 by Wiemer E.A.C., et al. Human peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disorders.