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- Table of Contents
PFKM Antibodies
AND PFKM ELISA kits, PFKM Proteins
Many biological assays use antibodies to detect PFKM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PFKM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PFKM antibodies...
Designing a Western blot for PFKM? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PFKM Western Blot GuideDesigning an IHC experiment for PFKM? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PFKM IHC GuidePFKM Infographic by Boster Bio
All PFKM Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00437-2
100 µg/vial
Cat # A00437-2
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M04370-1
100 μl/vial
Cat # M04370-1
100 μl/vial
SDS-PAGE
$265
Cat # PROTP08237
Starting from 20ug
Cat # PROTP08237
Starting from 20ug
PFKM Overview
Facts about ATP-dependent 6-phosphofructokinase, muscle type.
ATP-dependent 6-phosphofructokinase, muscle type (PFKM)
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the initial committing step of glycolysis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PFKM |
| Uniprot: | P08237 |
| Entrez: | 5213 |
Family
| Belongs to: |
|---|
| phosphofructokinase type A (PFKA) family |
Alternative Names
6-phosphofructokinase, muscle type; EC 2.7.1,6-phosphofructo-1-kinase; EC 2.7.1.11; GSD7; MGC8699; Muscle Phosphofructokinase; PFK1; PFK-1; PFKA; PFK-A; PFKM; PFKX; Phosphofructo-1-kinase isozyme A; Phosphofructokinase 1; phosphofructokinase, muscle; phosphofructokinase, polypeptide X; Phosphofructokinase-1; Phosphofructokinase-M; Phosphohexokinase
Molecular Weight
Mass (kDA):
85.183 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.11 |
| Sequence: | 12; NC_000012.12 (48105253..48146404) |
Subcellular Localizations
Cytoplasm.
Diseases
- Glycogen Storage Disease Type Vii
- Glycogen Storage Disease
- Neoplasms
- Myopathy
- Anemia
- Liver Diseases
- Drug-induced Liver Injury
- Down Syndrome
- Hypoxia
- Malignant Neoplasms
- Storage Disease
- Hypertrophy
- Muscle Weakness
Interacting Proteins
- PFKL
- SIAH1
Pathways
- Glycolysis
- Pathogenesis
- Transport
- Hibernation
- Cell Proliferation
- Gluconeogenesis
- Membrane Fusion
- Oxidative Phosphorylation
- Localization
- Reverse Transcription
PTMs
- Phosphorylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PFKM
bosterbio.com/bosterbio-gene-info-cards/PFKM
References
PMID: 1833270 by Yamasaki T., et al. Structure of the entire human muscle phosphofructokinase-encoding gene: a two-promoter system.
PMID: 2526045 by Sharma P.M., et al. Cloning and expression of a human muscle phosphofructokinase cDNA.