Profilin-4 Antibodies

AND PFN4 ELISA kits, Profilin-4 Proteins

Many biological assays use antibodies to detect Profilin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Profilin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Profilin-4 antibodies...

We validate the specificity of these antibodies to Profilin-4 by testing them on tissues known to express PFN4 positively and negatively. Browse below to find the PFN4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PFN4 Infographic by Boster Bio

All PFN4 Products

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Product

Figures

Specificity

Applications

Price

Human Profilin-4 Recombinant Protein

SDS-PAGE

$243
Cat # PROTQ8NHR9
Starting from 20ug

Profilin 4 (PFN4) (NM_199346) Human Over-expression Lysate

Human

$628
Cat # LS375189
20 µg, 100 µg

PFN4 Overview

Facts about Profilin-4.

PFN4 3D structure. Source: alphafold

Profilin-4 (PFN4)

Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Doesn't bind to actin (PubMed:19419568), contrary to other family members.

Gene Information

Human
Gene Name:	PFN4
Uniprot:	Q8NHR9
Entrez:	375189

Family

Belongs to:

profilin family

Alternative Names

profilin family, member 4; Profilin IV; profilin-4

Molecular Weight

Mass (kDA):
14.319 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (24114809..24124268, complement)

Tissue Specificity

Detected in testis (at protein level).

Subcellular Localizations

Cytoplasm, cytoskeleton.

Diseases

Neoplasms

Pathways

Cell Motility

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PFN4

References

PMID: 15591451 by Obermann H., et al. Novel testis-expressed profilin IV associated with acrosome biogenesis and spermatid elongation.

PMID: 19419568 by Behnen M., et al. Testis-expressed profilins 3 and 4 show distinct functional characteristics and localize in the acroplaxome-manchette complex in spermatids.