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Phactr1 Antibodies
AND Phactr1 ELISA kits, Phactr1 Proteins
Many biological assays use antibodies to detect Phactr1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phactr1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phactr1 antibodies...
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Phactr1 Overview
Facts about Phosphatase and actin regulator 1.
Phosphatase and actin regulator 1 (Phactr1)
Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in the formation of tubules by endothelial cells.
Regulates PPP1CA activity. Required for normal cell survival (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Phactr1 |
| Uniprot: | Q2M3X8 |
| Entrez: | 218194 |
Family
| Belongs to: |
|---|
| phosphatase and actin regulator family |
Alternative Names
dJ257A7.2; KIAA1733MGC126577; MGC126575; phosphatase and actin regulator 1; RPEL repeat containing 1; RPEL; RPEL1
Molecular Weight
Mass (kDA):
66.286 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 13|13 A4 |
| Sequence: | 13; |
Diseases
- Infarction
- Myocardial Infarction
- Coronary Artery Disease
- Coronary Heart Disease
- Stenosis
- Diabetic Angiopathies
- Cardiovascular Diseases
- Common Migraine
- Cerebrovascular Accident
- Headache
- Calcification Of Coronary Artery
- Brain Injuries
Pathways
- Gliogenesis
- Neurogenesis
- Nuclear Import
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Phactr1
bosterbio.com/bosterbio-gene-info-cards/Phactr1
References
PMID: 16359841 by de Chaldee M., et al. Capucin: a novel striatal marker down-regulated in rodent models of Huntington disease.
PMID: 22976292 by Wiezlak M., et al. G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly.