PH-interacting protein Antibodies

AND PHIP ELISA kits, PH-interacting protein Proteins

Many biological assays use antibodies to detect PH-interacting protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PH-interacting protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PH-interacting protein antibodies...

We validate the specificity of these antibodies to PH-interacting protein by testing them on tissues known to express PHIP positively and negatively. Browse below to find the PHIP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PHIP Infographic by Boster Bio

All PHIP Products

Product

Figures

Specificity

Applications

Price

Anti-PH-interacting protein PHIP Antibody

Human, Mouse

IF, IHC, ICC, WB

$405
Cat # A01555
100ul

PHIP Overview

Facts about PH-interacting protein.

PHIP 3D structure. Source: alphafold

PH-interacting protein (PHIP)

Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti- apoptotic activity through AKT1 phosphorylation and activation.

Plays a role in the regulation of cell morphology and cytoskeletal organization. .

Gene Information

Human
Gene Name:	PHIP
Uniprot:	Q8WWQ0
Entrez:	55023

Family

Belongs to:

No superfamily

Alternative Names

DCAF14; DDB1 and CUL4 associated factor 14; FLJ20705; FLJ45918; IRS-1 PH domain-binding protein; MGC90216; ndrp; PH-interacting protein; pleckstrin homology domain interacting protein; WD repeat-containing protein 11; WDR11

Molecular Weight

Mass (kDA):
206.689 kDA

Genomic Context


Human

Location:	6q14.1
Sequence:	6; NC_000006.12 (78934419..79078294, complement)

Tissue Specificity

Expressed in myeloma and epidermoid carcinoma cell lines.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Somatoform Disorder
Neoplasm Metastasis
Malnutrition
Melanoma
Communicable Diseases
Myeloid Leukemia, Chronic
Sarcoma
Myxoid Cyst
Parkinson Disease
Misalignment
Myeloid Leukemia

Cerebrovascular Accident
Dental Plaque
Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse
Hypoglycemia
Infective Disorder
Neuroblastoma
Left-sided Displacement Of Abomasum

Pathways

Protein Phosphorylation
Transport
Regeneration
Reverse Transcription
Sensitization
Cell Proliferation
Tricarboxylic Acid Cycle
Translation
Pathogenesis

Rna Interference
Glucose Transport
Localization

PTMs

Phosphorylation
Biotinylation

Reduction
Cleavage

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PHIP

References

PMID: 17636024 by Podcheko A., et al. Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.

PMID: 11018022 by Farhang-Fallah J., et al. Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.