PHLDB2 Antibodies

AND PHLDB2 ELISA kits, PHLDB2 Proteins

Many biological assays use antibodies to detect PHLDB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PHLDB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PHLDB2 antibodies...

We validate the specificity of these antibodies to PHLDB2 by testing them on tissues known to express PHLDB2 positively and negatively. Browse below to find the PHLDB2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PHLDB2 Infographic by Boster Bio

All PHLDB2 Products

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PHLDB2 (NM_001134437) Human Over-expression Lysate

Human

$960
Cat # LS090102
20 µg, 100 µg

PHLDB2 Overview

Facts about Pleckstrin homology-like domain family B member 2.

PHLDB2 3D structure. Source: alphafold

Pleckstrin homology-like domain family B member 2 (PHLDB2)

Appears to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity).

Gene Information

Human
Gene Name:	PHLDB2
Uniprot:	Q86SQ0
Entrez:	90102

Family

Belongs to:

No superfamily

Alternative Names

pleckstrin homology-like domain, family B, member 2

Molecular Weight

Mass (kDA):
142.158 kDA

Genomic Context


Human

Location:	3q13.2
Sequence:	3; NC_000003.12 (111732496..111976517)

Subcellular Localizations

Cytoplasm. Membrane; Peripheral membrane protein. Translocates to the plasma membrane at high levels of PtdIns(3,4,5)P3. At low levels of PtdIns(3,4,5)P3 is translocated to vesicular compartments.

Diseases

Tissue Adhesions
Carcinoma
Cell Invasion
Neuroblastoma
Malignant Squamous Cell Neoplasm
Tumor Angiogenesis
Head And Neck Neoplasms
Neoplasms

Headache
Liver Carcinoma
Head And Neck Carcinoma

Interacting Proteins

FLNA

Pathways

Localization
Transport
Cell Adhesion
Cell Proliferation
Cell Death
Cell Cycle
Cell Motility
Cell Growth

Angiogenesis
Rna Interference
Chromosome Segregation

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PHLDB2

References

PMID: 12376540 by Paranavitane V., et al. LL5beta is a phosphatidylinositol (3,4,5)-trisphosphate sensor that can bind the cytoskeletal adaptor, gamma-filamin.

PMID: 11001876 by Dowler S.J., et al. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.