PIEZO2 Antibodies

AND PIEZO2 ELISA kits, PIEZO2 Proteins

Many biological assays use antibodies to detect PIEZO2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIEZO2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIEZO2 antibodies...

We validate the specificity of these antibodies to PIEZO2 by testing them on tissues known to express PIEZO2 positively and negatively. Browse below to find the PIEZO2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIEZO2 Infographic by Boster Bio

All PIEZO2 Products

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Anti-PIEZO2 PIEZO1 Antibody

Western blot analysis of PIEZO2 in SK-N-SH cell lysate with PIEZO2 antibody at (A) 1 and (B) 2 μg/mL

WB Validation in Mouse Skeletal Muscle
Loading: 15 μg of mouse skeletal muscle lysate
Antibodies: PIEZO2 A01721-1701, 2 μg/mL , 1 h incubation at RT in 5% NFDM/TBST

Human, Mouse

ELISA, WB

$481
Cat # A01721
0.1 mg

Anti-Mallard Piezo2 Antibody

Mallard

$470
Cat # DZ41467
200 μl/vial

PIEZO2 Overview

Facts about Piezo-type mechanosensitive ion channel component 2.

Piezo-type mechanosensitive ion channel component 2 (PIEZO2)

Component of a mechanosensitive channel required for rapidly adapting automatically activated (MA) currents. Required for Merkel-cell mechanotransduction.

Plays a significant role in light- touch mechanosensation. .

Gene Information

Human
Gene Name:	PIEZO2
Uniprot:	Q9H5I5
Entrez:	63895

Family

Belongs to:

PIEZO (TC 1.A.75) family

Alternative Names

C18orf30; C18orf58; FAM38B; FAM38B2; family with sequence similarity 38, member B; family with sequence similarity 38, member B2; FLJ23144; FLJ23403; FLJ25916; FLJ34907; FLJ37734; FLJ45725; HsT748; HsT771; piezo-type mechanosensitive ion channel component 2; protein PIEZO2

Molecular Weight

Mass (kDA):
318.064 kDA

Genomic Context


Human

Location:	18p11.22-p11.21
Sequence:	18; NC_000018.10 (10670237..11149585, complement)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Pain
Neuroblastoma
Hyperalgesia
Thermal Hyperalgesia
Hyperalgesias, Mechanical

Pathways

Sensitization
Proprioception
Rna Interference

PTMs

Glycoprotein

Phosphoprotein

Research Areas

Alzheimers Research
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIEZO2

References

PMID: 27607563 by Mahmud A.A., et al. Loss of the proprioception and touch sensation channel PIEZO2 in siblings with a progressive form of contractures.

PMID: 27653382 by Chesler A.T., et al. The Role of PIEZO2 in Human Mechanosensation.