Protein pitchfork Antibodies

AND PIFO ELISA kits, Protein pitchfork Proteins

Many biological assays use antibodies to detect Protein pitchfork, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein pitchfork in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein pitchfork antibodies...

We validate the specificity of these antibodies to Protein pitchfork by testing them on tissues known to express PIFO positively and negatively. Browse below to find the PIFO antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIFO Infographic by Boster Bio

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PIFO Overview

Facts about Protein pitchfork.

PIFO 3D structure. Source: alphafold

Protein pitchfork (PIFO)

During primary cilia disassembly, involved in cilia disassembly. Required particularly to control cilia retraction as well as the liberation and duplication of the basal body/centrosome.

May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner. .

Gene Information

Human
Gene Name:	PIFO
Uniprot:	Q8TCI5
Entrez:	128344

Family

Belongs to:

No superfamily

Alternative Names

Protein pitchfork

Molecular Weight

Mass (kDA):
21.973 kDA

Genomic Context


Human

Location:	1p13.2
Sequence:	1; NC_000001.11 (111324663..111353017)

Subcellular Localizations

Cytoplasmic vesicle. Golgi apparatus, trans-Golgi network. Cytoplasm. Accumulates specifically at the basal body and ciliary necklace during the early steps of cilia assembly and disassembly, when structural, functional and regulatory proteins are delivered to cilia. At S phase, accumulates in vesicles and declines during mitosis.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIFO

References

PMID: 20643351 by Kinzel D., et al. Pitchfork regulates primary cilia disassembly and left-right asymmetry.