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- Table of Contents
Facts about Phosphoinositide-interacting protein.
Binds various phosphoinositide, including phosphatidylinositol 4,5- bisphosphate (PIP2), but not phosphatidylinositol (PI). .
Mouse | |
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Gene Name: | Pirt |
Uniprot: | Q8BFY0 |
Entrez: | 193003 |
Belongs to: |
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No superfamily |
phosphoinositide-interacting protein; phosphoinositide-interacting regulator of transient receptor potential channels; phosphoinositide-interacting regulator of TRPV1
Mass (kDA):
15.264 kDA
Mouse | |
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Location: | 11|11 B3 |
Sequence: | 11; |
Strongly expressed in most dorsal root ganglia (DRG) and trigeminal neurons. Expressed by most peptidergic (CGRP+) and non-peptidergic (IB4+) DRG neurons. Weakly expressed in other parts of the peripheral nervous system (PNS) including sympathetic and enteric neurons. Not expressed in the spinal cord.
PMID: 18455988 by Kim A.Y., et al. Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1.