PITPNM1 Antibodies

AND PITPNM1 ELISA kits, PITPNM1 Proteins

Many biological assays use antibodies to detect PITPNM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PITPNM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PITPNM1 antibodies...

We validate the specificity of these antibodies to PITPNM1 by testing them on tissues known to express PITPNM1 positively and negatively. Browse below to find the PITPNM1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PITPNM1 Infographic by Boster Bio

All PITPNM1 Products

Product

Figures

Specificity

Applications

Price

Anti-PITPNM1 Antibody

Human, Mouse, Rat

$405
Cat # A08128
100ul

NIR2 (PITPNM1) (NM_004910) Human Recombinant Protein

$1249
Cat # PROTO00562
20 µg

PITPNM1 Overview

Facts about Membrane-associated phosphatidylinositol transfer protein 1.

PITPNM1 3D structure. Source: alphafold

Membrane-associated phosphatidylinositol transfer protein 1 (PITPNM1)

Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis.

Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro).

Gene Information

Human
Gene Name:	PITPNM1
Uniprot:	O00562
Entrez:	9600

Family

Belongs to:

PtdIns transfer protein family

Alternative Names

DRES9NIR-2; Drosophila retinal degeneration B homolog; FLJ44997; membrane-associated phosphatidylinositol transfer protein 1; NIR2PITPNM; phosphatidylinositol transfer protein, membrane-associated 1Pyk2 N-terminal domain-interacting receptor 2; PITPnm 1; Rd9; RDGB; RDGB1; RDGBA; RDGBA1; retinal degeneration B alpha 1

Molecular Weight

Mass (kDA):
134.848 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (67491760..67505372, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody. Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets (PubMed:12225667). Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis (PubMed:15125835).

Diseases

Retinal Degeneration
Retinal Diseases
Sclerosis
Complete Hearing Loss
Primary Lateral Sclerosis
Disorder Of Eye
Cytopathic Effect
Nervousness

Amyotrophic Lateral Sclerosis
Trematode Infections

Interacting Proteins

TFCP2

Pathways

Transport
Cytokinesis
Phototransduction
Localization
Cell Division
Lipid Transport
Actin Cytoskeleton Reorganization
Cdp-choline Pathway
Mitosis
Cell Fate Determination
Protein Transport
Chromosome Segregation

Lipid Homeostasis
Interphase
Regulation Of Cytokinesis
Cell Morphogenesis
Pathogenesis
Rna Interference
Secretion

PTMs

Phosphorylation

Cleavage

Reduction

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PITPNM1

References

PMID: 9680295 by Rubboli F., et al. A mammalian homologue of the Drosophila retinal degeneration B gene: implications for the evolution of phototransduction mechanisms.

PMID: 10022914 by Lev S., et al. Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.