Phospholipase A2 Antibodies

AND PLA2G1B ELISA kits, Phospholipase A2 Proteins

Many biological assays use antibodies to detect Phospholipase A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phospholipase A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phospholipase A2 antibodies...

We validate the specificity of these antibodies to Phospholipase A2 by testing them on tissues known to express PLA2G1B positively and negatively. Browse below to find the PLA2G1B antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Phospholipase A2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PLA2G1B IHC Guide

PLA2G1B Infographic by Boster Bio

All PLA2G1B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Phospholipase A2 PLA2G1B Antibody

Western blot analysis of extracts of various cell lines, using PLA2G1B antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded mouse pancreas using PLA2G1B antibody at dilution of 1:100

Human, Mouse

IHC, WB

$405
Cat # A06738-1
100ul

Anti-PLA2G1B Reference Antibody (Diaccurate patent anti-sPLA2-GIB)

The purity of Anti-PLA2G1B Reference Antibody (Diaccurate patent anti-sPLA2-GIB)is more than 95%

Human, Mouse

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M06738
100 μg

PLA2G1B (NM_000928) Human Over-expression Lysate

Human

$628
Cat # LS005319
20 µg, 100 µg

Anti-PLA2G1B Antibody

Human, Mouse

ELISA, IF, IHC, WB

$370
Cat # A06738-2
100 μl/vial

PLA2G1B (NM_000928) Human Recombinant Protein

Coomassie blue staining of purified PLA2G1B protein

$1062
Cat # PROTP04054
20 µg

PLA2G1B Overview

Facts about Phospholipase A2.

PLA2G1B 3D structure. Source: alphafold

Phospholipase A2 (PLA2G1B)

PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid which serve as the precursors of signal molecules. .

Gene Information

Human
Gene Name:	PLA2G1B
Uniprot:	P04054
Entrez:	5319

Family

Belongs to:

phospholipase A2 family

Alternative Names

Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B; phospholipase A2; phospholipase A2, group IB (pancreas); PLA2; PLA2A; PLA2AMGC119834; PLA2EC 3.1.1.4; PLA2G1B; PPLA2; PPLA2MGC119835

Molecular Weight

Mass (kDA):
16.36 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (120322115..120327779, complement)

Subcellular Localizations

Secreted. secreted from pancreatic acinar cells in its inactive form.

Diseases

Diabetes Mellitus
Obesity
Impaired Glucose Tolerance
Diabetes Mellitus, Non-insulin-dependent
Inflammatory Response
Tissue Adhesions
Acute-phase Reaction
Malignant Neoplasms
Neoplasms
Liver Carcinoma
Inflammation
Respiratory Distress Syndrome, Adult

Respiratory Distress
Pancreatitis
Nervousness
Hyperglycemia
Acute Pancreatitis
Schizophrenia
Neurotoxicity Syndromes

Pathways

Secretion
Cell Migration
Inflammatory Response
Cell Death
Acute-phase Response
Cell Proliferation
Insulin Secretion
Fatty Acid Oxidation
Cell Adhesion
Acute Inflammatory Response
Gene Silencing
Aging
Immune Response

Activation Of Mapk Activity
Cell Division
Chemotaxis
Cell Cycle
Arachidonic Acid Secretion
Seminal Vesicle Development
Cell Differentiation

PTMs

Cleavage
Oxidation

Phosphorylation
Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLA2G1B

References

PMID: 3028739 by Seilhamer J.J., et al. Pancreatic phospholipase A2: isolation of the human gene and cDNAs from porcine pancreas and human lung.

PMID: 7060561 by Grataroli R., et al. Studies on prophospholipase A2 and its enzyme from human pancreatic juice. Catalytic properties and sequence of the N-terminal region.