PNPLA8 Antibodies

AND PNPLA8 ELISA kits, PNPLA8 Proteins

Many biological assays use antibodies to detect PNPLA8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PNPLA8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PNPLA8 antibodies...

We validate the specificity of these antibodies to PNPLA8 by testing them on tissues known to express PNPLA8 positively and negatively. Browse below to find the PNPLA8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PNPLA8? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PNPLA8 IHC Guide

PNPLA8 Infographic by Boster Bio

All PNPLA8 Products

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Anti-PNPLA8/Ipla2 Gamma Antibody

Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma

Human, Mouse

IHC, WB

$335
Cat # A30583
100ul

PNPLA8 Overview

Facts about Calcium-independent phospholipase A2-gamma.

PNPLA8 3D structure. Source: alphafold

Calcium-independent phospholipase A2-gamma (PNPLA8)

Calcium-independent phospholipase A2, which catalyzes the hydrolysis of this sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.

Gene Information

Human
Gene Name:	PNPLA8
Uniprot:	Q9NP80
Entrez:	50640

Family

Belongs to:

No superfamily

Alternative Names

calcium-independent phospholipase A2-gamma; EC 3.1.1.5; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2 gamma; IPLA22; IPLA2-2; iPLA2-gamma; IPLA2GIPLA2(GAMMA); membrane-associated calcium-independent phospholipase A2 gamma; patatin-like phospholipase domain containing 8; Patatin-like phospholipase domain-containing protein 8; PNPLA-gamma

Molecular Weight

Mass (kDA):
88.477 kDA

Genomic Context


Human

Location:	7q31.1
Sequence:	7; NC_000007.14 (108470417..108528178, complement)

Tissue Specificity

Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Cytoplasm, perinuclear region.

Diseases

Obesity

Pathways

Cell Death
Cell Differentiation

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PNPLA8

References

PMID: 10833412 by Tanaka H., et al. A novel intracellular membrane-bound calcium-independent phospholipase A(2).

PMID: 10744668 by Mancuso D.J., et al. The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium- independent phospholipase A(2).