This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
POU2F1 Antibodies
AND POU2F1 ELISA kits, POU2F1 Proteins
Many biological assays use antibodies to detect POU2F1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POU2F1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POU2F1 antibodies...
Designing a Western blot for POU2F1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the POU2F1 Western Blot GuideDesigning an IHC experiment for POU2F1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the POU2F1 IHC GuidePOU2F1 Infographic by Boster Bio
All POU2F1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1003
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1003
1 kit, containing one 96-well plate and all necessary reagents
POU2F1 Overview
Facts about POU domain, class 2, transcription factor 1.
POU domain, class 2, transcription factor 1 (POU2F1)
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of these genes for some small nuclear RNAs (snRNA) and of genes like those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity).
In the event of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby allowing the transcription of the viral immediate early genes. .
Gene Information
| Human | |
|---|---|
| Gene Name: | POU2F1 |
| Uniprot: | P14859 |
| Entrez: | 5451 |
Family
| Belongs to: |
|---|
| POU transcription factor family |
Alternative Names
FLJ42836; NF-A1; Oct-1; OCT1class 2, transcription factor 1; OTF1; POU class 2 homeobox 1; POU domain class 2, transcription factor 1; POU2F1
Molecular Weight
Mass (kDA):
76.472 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q24.2 |
| Sequence: | 1; NC_000001.11 (167220878..167427345) |
Tissue Specificity
Ubiquitous. Isoform 2 is lymphocyte-specific.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Leukemia
- Mammary Neoplasms
- Malignant Neoplasms
- Carcinoma
- Myeloid Leukemia, Chronic
- Liver Carcinoma
- Myeloid Leukemia
- Hiv Infections
- Inflammation
- Tissue Adhesions
- Neurofibromatosis 1
Interacting Proteins
- PLK3
- POGZ
- POU6F2
- PRR20D
- SP1
- SP4
Pathways
- Cell Cycle
- Dna Replication
- Transport
- Methylation
- Localization
- Immune Response
- Pathogenesis
- Cell Growth
- S Phase
- Cell Differentiation
- Cell Proliferation
- Cell Death
- Secretion
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Acetylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POU2F1
bosterbio.com/bosterbio-gene-info-cards/POU2F1
References
PMID: 2905684 by Sturm R.A., et al. The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.
PMID: 12663137 by Luchina N.N., et al. Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2.