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- Table of Contents
PPA2 Antibodies
AND PPA2 ELISA kits, PPA2 Proteins
Many biological assays use antibodies to detect PPA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPA2 antibodies...
Designing a Western blot for PPA2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PPA2 Western Blot GuideDesigning an IHC experiment for PPA2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PPA2 IHC GuidePPA2 Infographic by Boster Bio
All PPA2 Products
Product
Figures
Specificity
Applications
Price
PPA2 Overview
Facts about Inorganic pyrophosphatase 2, mitochondrial.
Inorganic pyrophosphatase 2, mitochondrial (PPA2)
Hydrolyzes inorganic pyrophosphate (PubMed:27523597). This activity is essential for proper regulation of mitochondrial membrane potential, and mitochondrial organization and function (PubMed:27523598).
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Gene Information
| Human | |
|---|---|
| Gene Name: | PPA2 |
| Uniprot: | Q9H2U2 |
| Entrez: | 27068 |
Family
| Belongs to: |
|---|
| PPase family |
Alternative Names
EC 3.6.1.1; FLJ20459; MGC49850; mitochondrial; pyrophosphatase (inorganic) 2
Molecular Weight
Mass (kDA):
37.92 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q24 |
| Sequence: | 4; NC_000004.12 (105369077..105474070, complement) |
Tissue Specificity
Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.
Subcellular Localizations
Mitochondrion.
Diseases
- Neoplasm Metastasis
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Prostate
- Atherosclerosis
- Prostatic Neoplasms
- Mitochondrial Dna Depletion
- Hepatitis, Chronic
- Metastatic Malignant Neoplasm To The Lymph Node
- Hepatitis C, Chronic
- Benign Prostatic Hypertrophy
- Carcinoma
Pathways
- Cell Cycle
- Cytokinesis
- Mitosis
- Transport
- Cell Division
- Interphase
- Cell Growth
- Protein Phosphorylation
- Hyperphosphorylation
- Habituation
- Virulence
- Anaphase
- Cell Cycle Arrest
PTMs
- Phosphorylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPA2
bosterbio.com/bosterbio-gene-info-cards/PPA2
References
PMID: 15210126 by Afjehi-Sadat L., et al. Hypothetical proteins with putative enzyme activity in human amnion, lymphocyte, bronchial epithelial and kidney cell lines.
PMID: 27523598 by Guimier A., et al. Biallelic PPA2 mutations cause sudden unexpected cardiac arrest in infancy.