PPARA Antibodies

AND PPARA ELISA kits, PPARA Proteins

Many biological assays use antibodies to detect PPARA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPARA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPARA antibodies...

We validate the specificity of these antibodies to PPARA by testing them on tissues known to express PPARA positively and negatively. Browse below to find the PPARA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PPARA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PPARA Western Blot Guide

Designing an IHC experiment for PPARA? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PPARA IHC Guide

PPARA Infographic by Boster Bio

All PPARA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PPAR alpha/PPARA Antibody Picoband®

12 Citations

Western blot analysis of PPAR alpha/PPARA using anti-PPAR alpha/PPARA antibody (A00600-2)

Flow Cytometry analysis of HepG2 cells using anti-PPAR alpha/PPARA antibody (A00600-2)

Puerarin regulates hepatic fatty acid metabolism

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00600-2
100 μg/vial

PPAR alpha (PPARA) (NM_001001928) Human Over-expression Lysate

PPAR alpha (PPARA) Human Over-expression Lysates NM_001001928

Human

$960
Cat # LS005465
20 µg, 100 µg

Anti-PPARA Antibody

Fluorescent image of Hela cells stained with PPARA Antibody

Western blot analysis of lysates from Hela, Jurkat, mouse NIH/3T3 cell line (from left to right), using PPARA Antibody

Immunohistochemical analysis of paraffin-embedded H

Human, Mouse

Flow Cytometry, IF, IHC-P, WB

$299
Cat # M00600
80 µl

PPARA Overview

Facts about Peroxisome proliferator-activated receptor alpha.

PPARA 3D structure. Source: alphafold

Peroxisome proliferator-activated receptor alpha (PPARA)

Ligand-activated transcription element. Key regulator of lipid metabolism.

Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety.

Gene Information

Human
Gene Name:	PPARA
Uniprot:	Q07869
Entrez:	5465

Family

Belongs to:

nuclear hormone receptor family

Alternative Names

alpha; hPPAR; NR1C1; NR1C1MGC2237; Nuclear receptor subfamily 1 group C member 1; peroxisome proliferator-activated receptor alpha; PPAR alpha; PPARA; PPARalpha; PPAR-alpha; PPARMGC2452

Molecular Weight

Mass (kDA):
52.225 kDA

Genomic Context


Human

Location:	22q13.31
Sequence:	22; NC_000022.11 (46150526..46243756)

Tissue Specificity

Skeletal muscle, liver, heart and kidney.

Subcellular Localizations

Nucleus.

Diseases

Diabetes Mellitus
Obesity
Diabetes Mellitus, Non-insulin-dependent
Cardiovascular Diseases
Insulin Resistance
Inflammation
Atherosclerosis
Coronary Artery Disease
Malignant Neoplasms
Fatty Liver
Hypertensive Disease
Neoplasms
Heart Diseases

Myocardial Ischemia
Steatohepatitis
Steatosis
Dyslipidemias
Hypertrophy
Tissue Adhesions
Insulin Sensitivity

Interacting Proteins

GRB2
NCOR1
NR1H3

Pathways

Fatty Acid Oxidation
Pathogenesis
Transport
Cell Proliferation
Secretion
Immune Response
Glucose Homeostasis
Fatty Acid Transport
Methylation
Inflammatory Response
Translation
Cell Adhesion
Cell Activation

Tissue Development
Cell Differentiation
Parturition
Fatty Acid Beta-oxidation
Energy Homeostasis
Response To Fenofibrate
Aging

PTMs

Oxidation
Methylation

Reduction
Cleavage

Deacetylation

Research Areas

Cancer
mTOR Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPARA

References

PMID: 7684926 by Sher T., et al. cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor.

PMID: 7981125 by Mukherjee R., et al. Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators.