PPCDC Antibodies

AND PPCDC ELISA kits, PPCDC Proteins

Many biological assays use antibodies to detect PPCDC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPCDC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPCDC antibodies...

We validate the specificity of these antibodies to PPCDC by testing them on tissues known to express PPCDC positively and negatively. Browse below to find the PPCDC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPCDC Infographic by Boster Bio

All PPCDC Products

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Product

Figures

Specificity

Applications

Price

Human PPCDC Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ96CD2
Starting from 20ug

PPCDC (NM_021823) Human Over-expression Lysate

Human

$628
Cat # LS060490
20 µg, 100 µg

PPCDC Overview

Facts about Phosphopantothenoylcysteine decarboxylase.

PPCDC 3D structure. Source: alphafold

Phosphopantothenoylcysteine decarboxylase (PPCDC)

Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'- phosphopantotheine.

Gene Information

Human
Gene Name:	PPCDC
Uniprot:	Q96CD2
Entrez:	60490

Family

Belongs to:

HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily

Alternative Names

coaC; EC 4.1.1.36; FLJ14585; MDS018; phosphopantothenoylcysteine decarboxylase; PPC-DC

Molecular Weight

Mass (kDA):
22.395 kDA

Genomic Context


Human

Location:	15q24.2
Sequence:	15; NC_000015.10 (75023544..75060180)

Diseases

Autistic Disorder
Chromosomal Translocation

Interacting Proteins

FOXR1
PPIG
SREK1IP1
TXN2
WDYHV1

ZNF232

Pathways

Tissue Morphogenesis
Gene Silencing
Pathogenesis
Localization
Oogenesis
Secretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPCDC

References

PMID: 11923312 by Daugherty M., et al. Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics.

PMID: 15581364 by Strauss E., et al. Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent.