PPOX Antibodies

AND PPOX ELISA kits, PPOX Proteins

Many biological assays use antibodies to detect PPOX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPOX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPOX antibodies...

We validate the specificity of these antibodies to PPOX by testing them on tissues known to express PPOX positively and negatively. Browse below to find the PPOX antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PPOX? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PPOX IHC Guide

PPOX Infographic by Boster Bio

All PPOX Products

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Product

Figures

Specificity

Applications

Price

Anti-Protoporphyrinogen oxidase PPOX Antibody

Western blot analysis of extracts of various cell lines, using PPOX Antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded human colon carcinoma using PPOX antibody at dilution of 1:100

Human, Mouse

IHC, WB

$405
Cat # A01856
100ul

PPOX (NM_000309) Human Over-expression Lysate

PPOX Human Over-expression Lysates NM_000309

Human

$628
Cat # LS005498
20 µg, 100 µg

PPOX (NM_001122764) Human Recombinant Protein

Coomassie blue staining of purified PPOX protein

$1062
Cat # PROTP50336
20 µg

PPOX Overview

Facts about Protoporphyrinogen oxidase.

PPOX 3D structure. Source: alphafold

Protoporphyrinogen oxidase (PPOX)

Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. .

Gene Information

Human
Gene Name:	PPOX
Uniprot:	P50336
Entrez:	5498

Family

Belongs to:

protoporphyrinogen oxidase family

Alternative Names

EC 1.3.3.4; MGC8485; PPOVP; protoporphyrinogen oxidase; V290M; variegate porphyria

Molecular Weight

Mass (kDA):
50.765 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (161165824..161178277)

Tissue Specificity

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.

Diseases

Disorders Of Porphyrin Metabolism
Variegate Porphyria
Porphyrias, Hepatic
Acute Intermittent Porphyria
Erythropoietic Protoporphyria
Dermatologic Disorders
Porphyria Cutanea Tarda
Liver Diseases
Hypokinesia
Hereditary Coproporphyria
Porphyria, Erythropoietic

Acute Interstitial Pneumonia
Liver Carcinoma
Skin Symptom
Acute Erythroblastic Leukemia
Abdominal Pain
Hepatoerythropoietic Porphyria

Pathways

Excretion
Localization
Pathogenesis
Cell Differentiation
Keratinization
Transport
Aerobic Respiration
Protein Targeting
Metaphase
Oxidative Phosphorylation
Mitochondrial Transport

Translation
Metabolic Process
Protein Folding
Root Development
Vacuolar Acidification

PTMs

Oxidation

Research Areas

Diabetes Research

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPOX

References

PMID: 7713909 by Nishimura K., et al. Cloning of a human cDNA for protoporphyrinogen oxidase by complementation in vivo of a hemG mutant of Escherichia coli.

PMID: 8771201 by Dailey T.A., et al. Human protoporphyrinogen oxidase: expression, purification, and characterization of the cloned enzyme.