PPP1R11 Antibodies

AND PPP1R11 ELISA kits, PPP1R11 Proteins

Many biological assays use antibodies to detect PPP1R11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP1R11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP1R11 antibodies...

We validate the specificity of these antibodies to PPP1R11 by testing them on tissues known to express PPP1R11 positively and negatively. Browse below to find the PPP1R11 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP1R11 Infographic by Boster Bio

All PPP1R11 Products

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Product

Figures

Specificity

Applications

Price

Anti-PPP1R11/Tctex5 Antibody

5 Q&As

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PPP1R11 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC

$335
Cat # A10474
100ul

PPP1R11 (NM_021959) Human Recombinant Protein

Coomassie blue staining of purified PPP1R11 protein

$1249
Cat # PROTO60927
20 µg

PPP1R11 (NM_021959) Human Over-expression Lysate

Human

$628
Cat # LS006992
20 µg, 100 µg

Anti-PPP1R11 Antibody Picoband®

Western blot analysis of PPP1R11 using anti-PPP1R11 antibody (A10474-2)

Flow Cytometry analysis of MCF-7 cells using anti-PPP1R11 antibody (A10474-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A10474-2
100 µg/vial

PPP1R11 Overview

Facts about E3 ubiquitin-protein ligase PPP1R11.

PPP1R11 3D structure. Source: alphafold

E3 ubiquitin-protein ligase PPP1R11 (PPP1R11)

Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram- positive bacterial clearance by working, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901).

Inhibitor of protein phosphatase 1 (PubMed:9843442). .

Gene Information

Human
Gene Name:	PPP1R11
Uniprot:	O60927
Entrez:	6992

Family

Belongs to:

No superfamily

Alternative Names

HCG V; HCG-V; inhibitor-3; IPP3; protein phosphatase 1 regulatory subunit 11; protein phosphatase 1, regulatory (inhibitor) subunit 11; TCTE5; TCTEX5

Molecular Weight

Mass (kDA):
13.953 kDA

Genomic Context


Human

Location:	6p22.1
Sequence:	6; NC_000006.12 (30066864..30070333)

Tissue Specificity

Widely expressed.

Diseases

Sterility
Male Infertility
Neoplasms
Chromosome Inversion
Hemochromatosis
Von Hippel-lindau Syndrome
Persistant Generalized Lymphadenopathy
Dysequilibrium Syndrome
Abnormal Behavior
Mutation Abnormality
Neoplasms, Experimental
Maple Syrup Urine Disease

Down Syndrome
Aneuploidy
Carcinoma
Immunologic Deficiency Syndromes
Dyskinetic Syndrome
Bladder Neck Obstruction

Interacting Proteins

PPP1CB
PPP1CC

Pathways

Fertilization
Spermatogenesis
Protein Folding
Translation
Localization
Sperm Motility
Pachytene
Proteolysis
Acrosome Reaction
Transport
Cell Cycle
Interphase
Mating

Meiosis
Gastrulation
Cell Growth
Protein Phosphorylation
Golgi Localization
Immune Response
Cell Fate Determination

PTMs

Phosphorylation
Dephosphorylation

Methylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP1R11

References

PMID: 8781118 by Giffon T., et al. Cloning of a human homologue of the mouse Tctex-5 gene within the MHC class I region.

PMID: 8938444 by Lepourcelet M., et al. Systematic sequencing of the human HLA-A/HLA-F region: establishment of a cosmid contig and identification of a new gene cluster within 37 kb of sequence.