PPP1R12B Antibodies

AND PPP1R12B ELISA kits, PPP1R12B Proteins

Many biological assays use antibodies to detect PPP1R12B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP1R12B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP1R12B antibodies...

We validate the specificity of these antibodies to PPP1R12B by testing them on tissues known to express PPP1R12B positively and negatively. Browse below to find the PPP1R12B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP1R12B Infographic by Boster Bio

All PPP1R12B Products

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Specificity

Applications

Price

Myosin Phosphatase 2 (PPP1R12B) (NM_032104) Human Over-expression Lysate

Human

$628
Cat # LS004660
20 µg, 100 µg

Anti-PPP1R12B Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A11318-1
100 μl/vial

PPP1R12B Overview

Facts about Protein phosphatase 1 regulatory subunit 12B.

PPP1R12B 3D structure. Source: alphafold

Protein phosphatase 1 regulatory subunit 12B (PPP1R12B)

Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.

Gene Information

Human
Gene Name:	PPP1R12B
Uniprot:	O60237
Entrez:	4660

Family

Belongs to:

No superfamily

Alternative Names

MGC131980; MGC87886; Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; Myosin phosphatase-targeting subunit 2; MYPT 2 ; MYPT2FLJ40942; protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B

Molecular Weight

Mass (kDA):
110.404 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (202348699..202592702)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Along actomyosin filaments.

Diseases

Rhinorrhea
Allergic Rhinitis (disorder)
Rhinitis, Allergic, Perennial
Malignant Neoplasms
Neoplasms
Colorectal Neoplasms
Tumor Progression
Asthma

Allergy
Colorectal Cancer
Carcinogenesis

Interacting Proteins

PIK3R3

Pathways

Protein Phosphorylation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP1R12B

References

PMID: 9570949 by Fujioka M., et al. A new isoform of human myosin phosphatase targeting/regulatory subunit (MYPT2): cDNA cloning, tissue expression, and chromosomal mapping.

PMID: 11067852 by Arimura T., et al. Identification, characterization, and functional analysis of heart- specific myosin light chain phosphatase small subunit.