PPP2R1A Antibodies

AND PPP2R1A ELISA kits, PPP2R1A Proteins

Many biological assays use antibodies to detect PPP2R1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP2R1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP2R1A antibodies...

We validate the specificity of these antibodies to PPP2R1A by testing them on tissues known to express PPP2R1A positively and negatively. Browse below to find the PPP2R1A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PPP2R1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PPP2R1A Western Blot Guide

PPP2R1A Infographic by Boster Bio

All PPP2R1A Products

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Applications

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Anti-PPP2R1A Antibody Picoband®

1 Citations

Western blot analysis of PPP2R1A using anti-PPP2R1A antibody (A02822-2)

IHC analysis of PPP2R1A using anti-PPP2R1A antibody (A02822-2)

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # A02822-2
100 μg/vial

PPP2R1A (NM_014225) Human Over-expression Lysate

Human

$628
Cat # LS005518
20 µg, 100 µg

Human PPP2R1A Recombinant Protein

SDS-PAGE

$250
Cat # PROTP30153
Starting from 20ug

PPP2R1A Overview

Facts about Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform.

PPP2R1A 3D structure. Source: alphafold

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A)

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Gene Information

Human
Gene Name:	PPP2R1A
Uniprot:	P30153
Entrez:	5518

Family

Belongs to:

phosphatase 2A regulatory subunit A family

Alternative Names

Medium tumor antigen-associated 61 kDa protein; MGC786; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2AAALPHA; PP2A-Aalpha; PR65A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alphaisoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2, regulatory subunit A, alpha; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alphaisoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alphaisoform

Molecular Weight

Mass (kDA):
65.309 kDA

Genomic Context


Human

Location:	19q13.41
Sequence:	19; NC_000019.10 (52190052..52229518)

Subcellular Localizations

Cytoplasm. Nucleus. Chromosome, centromere. Lateral cell membrane. Cell projection, dendrite. Centromeric localization requires the presence of BUB1.

Diseases

Carcinoma
Malignant Neoplasms
Neoplasms
Ovarian Neoplasm
Cystadenocarcinoma, Serous
Endometrial Neoplasms
Endometrial Polyp
Adenocarcinoma, Clear Cell
Uterine Neoplasms
Mammary Neoplasms
Epithelial Ovarian Cancer
Carcinosarcoma
Carcinogenesis

Malignant Neoplasm Of Ovary
Carcinoma, Endometrioid
Cell Transformation, Neoplastic
Mucinous Adenocarcinoma
Endometrial Carcinoma
Melanoma
Malignant Neoplasm Of Breast

Interacting Proteins

AKT1
AMBRA1
ARHGEF7
AURKB
CCNG1

CIP2A
CSDC2
Nxn
PLA2G16
PPP2CA

PPP2R1B
PPP2R2A
PPP2R2B
PPP2R5A
PPP2R5B

PPP2R5C
PPP2R5D
PPP2R5E
PPP4C
PPP5C

RELA
STRN
TP53

Pathways

Pathogenesis
Methylation
Glycolysis
Transport
Cell Adhesion
Immune Response
Complement Activation
Muscle Contraction
Mammary Gland Development
Chromosome Segregation
Cell Cycle Arrest
Inflammatory Response
Nuclear Transport

Menstruation
Translation
Cell Cycle
Regulation Of Complement Activation
Mrna Processing
Interphase
Chromatin Remodeling

PTMs

Phosphorylation

Dephosphorylation

Methylation

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP2R1A

References

PMID: 2554323 by Walter G., et al. Molecular cloning and sequence of cDNA encoding polyoma medium tumor antigen-associated 61-kDa protein.

PMID: 2159327 by Hemmings B.A., et al. Alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure.