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PPP2R1B Antibodies
AND PPP2R1B ELISA kits, PPP2R1B Proteins
Many biological assays use antibodies to detect PPP2R1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP2R1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP2R1B antibodies...
Designing an IHC experiment for PPP2R1B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PPP2R1B IHC GuidePPP2R1B Infographic by Boster Bio
All PPP2R1B Products
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PPP2R1B Overview
Facts about Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform.
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B)
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PPP2R1B |
| Uniprot: | P30154 |
| Entrez: | 5519 |
Family
| Belongs to: |
|---|
| phosphatase 2A regulatory subunit A family |
Alternative Names
MGC26454; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A, subunit A, PR65-beta isoform; PP2A, subunit A, R1-beta isoform; PP2A-Abeta; PR65B; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; protein phosphatase 2, regulatory subunit A, beta; protein phosphatase 2, structural/regulatory subunit A, beta; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A betaisoform
Molecular Weight
Mass (kDA):
66.214 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.1 |
| Sequence: | 11; NC_000011.10 (111690273..111766389, complement) |
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Colorectal Cancer
- Malignant Neoplasm Of Ovary
- Malignant Neoplasm Of Breast
- Malignant Tumor Of Colon
- Mammary Neoplasms
- Carcinogenesis
- Cell Transformation, Neoplastic
- Melanoma
Interacting Proteins
- Clock
- PPP2CA
- PPP2R1A
- PPP2R2A
- PPP2R5A
- PPP2R5C
- PPP2R5D
- PPP2R5E
- RALA
- Unc5b
Pathways
- Pathogenesis
- Cell Cycle
- Localization
- Protein Phosphorylation
- Methylation
- Cell Migration
- Cell Cycle Arrest
- Inflammatory Response
- Cell Death
- Secretion
- Transport
- Cell Activation
- Gene Silencing
PTMs
- Phosphorylation
- Dephosphorylation
- Methylation
Research Areas
- Breast Cancer
- Protein Phosphatase
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP2R1B
bosterbio.com/bosterbio-gene-info-cards/PPP2R1B
References
PMID: 9795170 by Baysal B.E., et al. Genomic organization and precise physical location of protein phosphatase 2A regulatory subunit A beta isoform gene on chromosome band 11q23.
PMID: 9765152 by Wang S.S., et al. Alterations of the PPP2R1B gene in human lung and colon cancer.