PPT2 Antibodies

AND PPT2 ELISA kits, PPT2 Proteins

Many biological assays use antibodies to detect PPT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPT2 antibodies...

We validate the specificity of these antibodies to PPT2 by testing them on tissues known to express PPT2 positively and negatively. Browse below to find the PPT2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPT2 Infographic by Boster Bio

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PPT2 (NM_005155) Human Over-expression Lysate

PPT2 Human Over-expression Lysates NM_005155

Human

$628
Cat # LS009374
20 µg, 100 µg

PPT2 Overview

Facts about Lysosomal thioesterase PPT2.

PPT2 3D structure. Source: alphafold

Lysosomal thioesterase PPT2 (PPT2)

Removes thioester-linked fatty acyl groups from various substrates such as S-palmitoyl-CoA. Has the highest S- thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates.

But because of structural constraints, is unable to eliminate palmitate from peptides or proteins. .

Gene Information

Human
Gene Name:	PPT2
Uniprot:	Q9UMR5
Entrez:	9374

Family

Belongs to:

palmitoyl-protein thioesterase family

Alternative Names

C6orf8; DKFZp564P1516; EC 3.1.2; EC 3.1.2.-; G14; lysosomal thioesterase PPT2; palmitoyl-protein hydrolase 2; palmitoyl-protein thioesterase 2; PPT-2; S-thioesterase G14; VE-statin2

Molecular Weight

Mass (kDA):
34.225 kDA

Genomic Context


Human

Location:	6p21.32
Sequence:	6; NC_000006.12 (32153528..32163675)

Tissue Specificity

Broadly expressed, with highest levels in skeletal muscle.

Subcellular Localizations

Lysosome.

Diseases

Neuronal Ceroid-lipofuscinoses
Neurodegenerative Disorders
Infantile Neuronal Ceroid Lipofuscinosis
Lysosomal Storage Diseases
Muscle Spasticity
Myocardial Ischemia
Regurgitation
Juvenile Neuronal Ceroid Lipfuscinosis
Ataxia
Lung Diseases
Narcolepsy
Chronic Obstructive Airway Disease

Immunologic Deficiency Syndromes
Lung Diseases, Obstructive
Leukemia, Myelocytic, Acute
Histiocytosis
Lysosomal Storage Diseases, Nervous System
Lupus Erythematosus, Systemic

Pathways

Reverse Transcription
Transposition
Localization
Drug Resistance

PTMs

Palmitoylation
Glycosylation

Cleavage
Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPT2

References

PMID: 9341199 by Soyombo A.A., et al. Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity.

PMID: 10417332 by Aguado B., et al. Characterization of a human MHC class III region gene product with S- thioesterase activity.