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- Table of Contents
Designing an IHC experiment for PRDM2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PRDM2 IHC GuideFacts about PR domain zinc finger protein 2.
Binds to the macrophage-specific TPA-responsive element (MTE) of this HMOX1 (heme oxygenase 1) gene and may function as a transcriptional activator of this gene. .
| Human | |
|---|---|
| Gene Name: | PRDM2 |
| Uniprot: | Q13029 |
| Entrez: | 7799 |

| Belongs to: |
|---|
| class V-like SAM-binding methyltransferase superfamily |

PR domain zinc finger protein 2
Mass (kDA):
188.915 kDA

| Human | |
|---|---|
| Location: | 1p36.21 |
| Sequence: | 1; NC_000001.11 (13698874..13825079) |
Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3.
Nucleus.


PMID: 7538672 by Buyse I.M., et al. The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.
PMID: 9006946 by Liu L., et al. The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter.