Putative histone-lysine N-methyltransferase PRDM6 (PRDM6)

Putative histone methyltransferase that functions as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells.

Plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it's histone methyltransferase activity in vivo.