PR domain zinc finger protein 8 (PRDM8)

Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes like CYP17A1 and LHCGR (By similarity).

Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it's necessary for rod bipolar and form 2 OFF-cone bipolar cell survival (By similarity).