PREB Antibodies

AND PREB ELISA kits, PREB Proteins

Many biological assays use antibodies to detect PREB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PREB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PREB antibodies...

We validate the specificity of these antibodies to PREB by testing them on tissues known to express PREB positively and negatively. Browse below to find the PREB antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PREB? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PREB Western Blot Guide

PREB Infographic by Boster Bio

All PREB Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PREB Antibody Picoband®

Western blot analysis of PREB using anti-PREB antibody (A04946)

Human

$370
Cat # A04946
100 μg/vial

Anti-PREB Rabbit Monoclonal Antibody

Western blot analysis of PREB expression in Raji cell lysate

Human

IF, IHC, ICC, WB

$370
Cat # M04946
100 μl/vial

PREB (NM_013388) Human Over-expression Lysate

Human

$628
Cat # LS010113
20 µg, 100 µg

Anti-Immunoglobulin iota chain VPREB1 Antibody

Western blot (WB) analysis of VPREB1 pAb at 1:500 dilution
Lane1:Myla2059 whole cell lysate(40ug)
Lane2:HuT78 whole cell lysate(40ug)
Lane3:K562 whole cell lysate(40ug)

Human

$405
Cat # A10453
100ul

PREB Overview

Facts about Prolactin regulatory element-binding protein.

PREB 3D structure. Source: alphafold

Prolactin regulatory element-binding protein (PREB)

Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore necessary for the formation of COPII transport vesicles from the ER.

Gene Information

Human
Gene Name:	PREB
Uniprot:	Q9HCU5
Entrez:	10113

Family

Belongs to:

No superfamily

Alternative Names

MGC3467; PREB; prolactin regulatory binding-element protein; prolactin regulatory element binding; prolactin regulatory element-binding protein; SEC12; SEC12Mammalian guanine nucleotide exchange factor mSec12

Molecular Weight

Mass (kDA):
45.468 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (27130756..27134675, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Concentrates at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).

Diseases

Pituitary Diseases
Neoplasms
Adenoma
Eating Disorders
Mood Disorders
Functionless Pituitary Neoplasm
Posterior Reversible Encephalopathy Syndrome
Nervousness
Pituitary Neoplasms
Bipolar Disorder
Prolactinoma
Chromosome 2, Trisomy 2p

Anxiety Disorders
Partial Trisomy
Obsessive-compulsive Disorder
Atherosclerosis
Diabetes Mellitus
Brain Neoplasms

Pathways

Secretion
Insulin Secretion
Glucose Homeostasis
Response To Camp
Cell Cycle
Cell Fate Determination
Mating

Rna Interference
Sexual Reproduction

PTMs

Nitration

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PREB

References

PMID: 10920239 by Taylor Clelland C.L., et al. Cloning and characterization of human PREB; a gene that maps to a genomic region associated with trisomy 2p syndrome.

PMID: 12735795 by Edgar A.J.; The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12.