Proteoglycan 3 Antibodies

AND PRG3 ELISA kits, Proteoglycan 3 Proteins

Many biological assays use antibodies to detect Proteoglycan 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proteoglycan 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proteoglycan 3 antibodies...

We validate the specificity of these antibodies to Proteoglycan 3 by testing them on tissues known to express PRG3 positively and negatively. Browse below to find the PRG3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRG3 Infographic by Boster Bio

All PRG3 Products

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PRG3 (NM_006093) Human Recombinant Protein

Coomassie blue staining of purified PRG3 protein

$1249
Cat # PROTQ9Y2Y8
20 µg

PRG3 (NM_006093) Human Over-expression Lysate

Human

$628
Cat # LS010394
20 µg, 100 µg

PRG3 Overview

Facts about Proteoglycan 3.

PRG3 3D structure. Source: alphafold

Proteoglycan 3 (PRG3)

Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.

Gene Information

Human
Gene Name:	PRG3
Uniprot:	Q9Y2Y8
Entrez:	10394

Family

Belongs to:

No superfamily

Alternative Names

Eosinophil Major Basic Protein Homolog; MBP2; MBPH; Prepro-Major Basic Protein Homolog; Prepro-MBPH; PRG3; Proteoglycan 3

Molecular Weight

Mass (kDA):
25.406 kDA

Genomic Context


Human

Location:	11q12.1
Sequence:	11; NC_000011.10 (57376769..57381150, complement)

Tissue Specificity

Expressed in bone marrow. Not detected in placenta.

Subcellular Localizations

Cytoplasmic granule. Localized to the eosinophil secondary granule.

Diseases

Neoplasms
Nervousness
Neuroblastoma
Cell Transformation, Neoplastic
Helminthiasis
Dna Degradation, Apoptotic
Malignant Tumor Of Colon
Lesion Of Brain

Malignant Neoplasms
Asthma
Crohn Disease

Pathways

Cell Death
Programmed Cell Death
Cell Cycle
Spinal Cord Development
Cell Cycle Arrest

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRG3

References

PMID: 10318872 by Plager D.A., et al. A novel and highly divergent homolog of human eosinophil granule major basic protein.

PMID: 11170744 by Plager D.A., et al. Comparative structure, proximal promoter elements, and chromosome location of the human eosinophil major basic protein genes.