PROZ Antibodies

AND PROZ ELISA kits, PROZ Proteins

Many biological assays use antibodies to detect PROZ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PROZ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PROZ antibodies...

We validate the specificity of these antibodies to PROZ by testing them on tissues known to express PROZ positively and negatively. Browse below to find the PROZ antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PROZ Infographic by Boster Bio

All PROZ Products

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Product

Figures

Specificity

Applications

Price

Anti-Protein Z PROZ Monoclonal Antibody

3 Q&As

Human

ELISA, WB

$399
Cat # A06491
100μl

Anti-Vitamin K-dependent protein Z PROZ Antibody

Western blot analysis of extracts of various cell lines, using PROZ antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A06491-1
100ul

Protein Z (PROZ) (NM_003891) Human Over-expression Lysate

Human

$628
Cat # LS008858
20 µg, 100 µg

PROZ Overview

Facts about Vitamin K-dependent protein Z.

PROZ 3D structure. Source: alphafold

Vitamin K-dependent protein Z (PROZ)

Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.

Gene Information

Human
Gene Name:	PROZ
Uniprot:	P22891
Entrez:	8858

Family

Belongs to:

peptidase S1 family

Alternative Names

protein Z, vitamin K-dependent plasma glycoprotein; PZ; vitamin K-dependent protein Z

Molecular Weight

Mass (kDA):
44.744 kDA

Genomic Context


Human

Location:	13q34
Sequence:	13; NC_000013.11 (113155864..113172386)

Tissue Specificity

Plasma.

Subcellular Localizations

Secreted.

Diseases

Cardiovascular Diseases
Salmonella Infections
Variable Number Tandem Repeat
Fracture
Venous Thromboembolism
Hemorrhage
Cerebrovascular Accident
5,10-methylenetetrahydrofolate Reductase Deficiency

Inflammation
Thromboembolism
Dysequilibrium Syndrome

Pathways

Coagulation
Transport
Proline Transport
Translation
Amino Acid Transport
Branched-chain Amino Acid Transport

Glycine Betaine Transport

PTMs

Cleavage on pair of basic residues
Disulfide bond

Gamma-carboxyglutamic acid
Glycoprotein

Hydroxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PROZ

References

PMID: 2244898 by Ichinose A., et al. Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein.

PMID: 9578570 by Fujimaki K., et al. The gene for human protein Z is localized to chromosome 13 at band q34 and is coded by eight regular exons and one alternative exon.