Prr5l Antibodies

AND Prr5l ELISA kits, Prr5l Proteins

Many biological assays use antibodies to detect Prr5l, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prr5l in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prr5l antibodies...

We validate the specificity of these antibodies to Prr5l by testing them on tissues known to express Prr5l positively and negatively. Browse below to find the Prr5l antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: Htatsf1

Prr5l Infographic by Boster Bio

All Prr5l Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Proline-rich protein 5-like PRR5L Antibody

Western blot analysis of PRR5L in 3T3 cell lysate with PRR5L antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunocytochemistry of PPR5L in 293 cells with PPR5L antibody at 10 μg/mL

Immunofluorescence of PPR5L in3T3 cells with PPR5L antibody at 20 μg/mL

Human, Mouse

ELISA, IF, ICC, WB

$481
Cat # A10603
0.1 mg

FLJ14213 (PRR5L) (NM_024841) Human Over-expression Lysate

FLJ14213 (PRR5L) Human Over-expression Lysates NM_001160169

Human

$628
Cat # LS079899
20 µg, 100 µg

Prr5l Overview

Facts about Proline-rich protein 5-like.

Proline-rich protein 5-like (Prr5l)

Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton (By similarity). Regulates the activity of this mTORC2 complex at a substrate-specific manner preventing instance the particular phosphorylation of PKCs and thereby controlling cell migration (PubMed:22609986).

Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress. Needed for ZFP36 localization into cytoplasmic stress granule (SG) and P-body (PB) in response to stress.

Gene Information

Mouse
Gene Name:	Prr5l
Uniprot:	A2AVJ5
Entrez:	72446

Family

Belongs to:

PROTOR family

Alternative Names

FLJ14213MGC16218; FLJ22630; proline rich 5 like; Protein observed with Rictor-2; protor-2; PROTOR2proline-rich protein 5-like

Molecular Weight

Mass (kDA):
40.982 kDA

Genomic Context


Mouse

Location:	2\|2 E2
Sequence:	2;

Diseases

Sclerosis
Fibrosis
Pulmonary Fibrosis
Tuberous Sclerosis

Pathways

Cell Migration
Cell Death
Induction Of Apoptosis
Cell Growth
Fibroblast Migration

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Prr5l

References

PMID: 22609986 by Gan X., et al. PRR5L degradation promotes mTORC2-mediated PKC-delta phosphorylation and cell migration downstream of Galpha12.