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Prxl2b Antibodies
AND Prxl2b ELISA kits, Prxl2b Proteins
Many biological assays use antibodies to detect Prxl2b, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prxl2b in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prxl2b antibodies...
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Prxl2b Overview
Facts about Prostamide/prostaglandin F synthase.
Prostamide/prostaglandin F synthase (Prxl2b)
Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) into prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha).
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Gene Information
| Mouse | |
|---|---|
| Gene Name: | Prxl2b |
| Uniprot: | Q9DB60 |
| Entrez: | 66469 |
Family
| Belongs to: |
|---|
| peroxiredoxin-like PRXL2 family |
Alternative Names
Prostamide/prostaglandin F synthase
Molecular Weight
Mass (kDA):
21.67 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 4|4 E2 |
| Sequence: | 4; |
Tissue Specificity
Mainly present in brain and spinal cord. In spinal cord, present in the superficial layer of the dorsal horn, in motor neurons of the ventral horn and in glia of the white matter of the spinal cord. In brain, expressed preferentially in the white matter bundles of the entire CNS of adult with less marked expression in neuronal cell bodies. Colocalizes with MBP in myelin sheaths but not in axons. Localizes to myelin sheaths (at protein level).
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Prxl2b
bosterbio.com/bosterbio-gene-info-cards/Prxl2b
References
PMID: 18006499 by Moriuchi H., et al. Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily.
PMID: 20950588 by Yoshikawa K., et al. Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system.