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We validate the specificity of these antibodies to PSENEN by testing them on tissues known to express PSENEN positively and negatively. Browse below to find the PSENEN antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.
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Facts about Gamma-secretase subunit PEN-2.
PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111). .
gamma-secretase subunit PEN-2; MSTP064; PEN-2; PEN2hematopoietic stem/progenitor cells protein MDS033; presenilin enhancer 2 homolog (C. elegans); Presenilin enhancer protein 2; PSENEN
|Sequence:||19; NC_000019.10 (35745651..35747519)|
Widely expressed. Expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Predominantly located in the endoplasmic reticulum and in the cis-Golgi.