PTBP1 Antibodies

AND PTBP1 ELISA kits, PTBP1 Proteins

Many biological assays use antibodies to detect PTBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTBP1 antibodies...

We validate the specificity of these antibodies to PTBP1 by testing them on tissues known to express PTBP1 positively and negatively. Browse below to find the PTBP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTBP1 Infographic by Boster Bio

All PTBP1 Products

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Specificity

Applications

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Anti-PTBP1 Monoclonal Antibody

2 Q&As

All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature

Western blot analysis of PTBP1 expression in Daudi cell lysate

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M01798
100 μl

Anti-PTBP1 Antibody Picoband®

2 Citations

Western blot analysis of PTBP1 using anti-PTBP1 antibody (A01798)

IHC analysis of PTBP1 using anti-PTBP1 antibody (A01798)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01798
100 μg/vial

Anti-PTBP1 Antibody Picoband®(monoclonal, 3H12)

Western blot analysis of PTBP1 using anti-PTBP1 antibody (M01798-1)

IHC analysis of PTBP1 using anti-PTBP1 antibody (M01798-1)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01798-1
100 μg/vial

PTBP1 (NM_002819) Human Over-expression Lysate

PTBP1 Human Over-expression Lysates NM_002819

Human

$628
Cat # LS005725
20 µg, 100 µg

PTBP1 Overview

Facts about Polypyrimidine tract-binding protein 1.

PTBP1 3D structure. Source: alphafold

Polypyrimidine tract-binding protein 1 (PTBP1)

Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns.

May promote RNA looping when bound to two different polypyrimidine tracts at the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA.

Gene Information

Human
Gene Name:	PTBP1
Uniprot:	P26599
Entrez:	5725

Family

Belongs to:

No superfamily

Alternative Names

Heterogeneous nuclear ribonucleoprotein I; heterogeneous nuclear ribonucleoprotein polypeptide I; hnRNP I; HNRNPI; HNRNP-I; HNRPI; MGC10830; MGC8461; polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoproteinI); polypyrimidine tract binding protein 1; polypyrimidine tract-binding protein 1; pPTB; PTB-1; PTB2; PTB3; PTB4; PTB57 kDa RNA-binding protein PPTB-1; PTB-T; RNA-binding protein

Molecular Weight

Mass (kDA):
57.221 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (797452..812316)

Subcellular Localizations

Nucleus.

Diseases

Nervousness
Malignant Neoplasms
Neoplasms
Neuroblastoma
Malignant Neoplasm Of Breast
Glioma
Adenocarcinoma
Cell Transformation, Neoplastic
Liver Carcinoma
Glioblastoma
Liver Diseases
Malnutrition

Insulinoma
Myasthenic Syndromes, Congenital
Myopathy
Multiple Myeloma
Mammary Neoplasms
Stress, Psychological

Interacting Proteins

PCBP1
QKI
RBM10
SFPQ
SNRPA

Pathways

Translation
Localization
Secretion
Cell Proliferation
Insulin Secretion
Rna Splicing
Rna Processing
Neurogenesis
Mrna Processing
Synapse Maturation
Cell Activation
Cell Migration
Gene Silencing

T Cell Activation
Brain Development
M Phase
Oxidative Phosphorylation
Nuclear Export
Rna Surveillance
System Development

PTMs

Phosphorylation
Cleavage

Biotinylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTBP1

References

PMID: 1906035 by Gil A., et al. Characterization of cDNAs encoding the polypyrimidine tract-binding protein.

PMID: 1906036 by Patton J.G., et al. Characterization and molecular cloning of polypyrimidine tract- binding protein: a component of a complex necessary for pre-mRNA splicing.