Protein patched homolog 2 Antibodies

AND PTCH2 ELISA kits, Protein patched homolog 2 Proteins

Many biological assays use antibodies to detect Protein patched homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein patched homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein patched homolog 2 antibodies...

We validate the specificity of these antibodies to Protein patched homolog 2 by testing them on tissues known to express PTCH2 positively and negatively. Browse below to find the PTCH2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTCH2 Infographic by Boster Bio

All PTCH2 Products

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Anti-PTCH2 Antibody Picoband®

1 Citations 2 Q&As

Anti-PTCH2 antibody, PA1859, Western blottingWB: HELA Cell Lysate

TGF-β1/SMAD3 promotes the nuclear translocation and expression
of GLI2

Human, Mouse

$370
Cat # PA1859
100 μg/vial

Anti-PTCH2 Antibody Picoband®

Western blot analysis of PTCH2 using anti-PTCH2 antibody (A06375-1)

IHC analysis of PTCH2 using anti-PTCH2 antibody (A06375-1)

Human

IF, IHC, ICC, WB

$370
Cat # A06375-1
100 μg/vial

Anti-PTCH2 Mouse Monoclonal Antibody [Clone ID: OTI8B5]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTCH2 (Right lane) cDNA for 48 hrs and lysed

Human, Mouse

$523
Cat # M06375
100 µl

PTCH2 (NM_003738) Human Over-expression Lysate

Human

$960
Cat # LS008643
20 µg, 100 µg

PTCH2 Overview

Facts about Protein patched homolog 2.

PTCH2 3D structure. Source: alphafold

Protein patched homolog 2 (PTCH2)

May have a role in epidermal development. May act as a receptor for Sonic hedgehog (SHH).

Gene Information

Human
Gene Name:	PTCH2
Uniprot:	Q9Y6C5
Entrez:	8643

Family

Belongs to:

patched family

Alternative Names

patched (Drosophila) homolog 2; Patched 2; patched homolog 2 (Drosophila); patched homolog 2; protein patched homolog 2; ptc2; PTCH2

Molecular Weight

Mass (kDA):
130.544 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (44819844..44843253, complement)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Neoplasms
Carcinoma
Basal Cell Carcinoma
Malignant Neoplasms
Cell Transformation, Neoplastic
Medulloblastoma
Basal Cell Nevus Syndrome
Malignant Neoplasm Of Pancreas
Skin Neoplasms
Malignant Neoplasm Of Stomach
Malignant Paraganglionic Neoplasm
Carcinogenesis
Brain Neoplasms

Malignant Neoplasm Of Breast
Stomach Neoplasms
Neoplasm Invasiveness
Esophageal Neoplasms
Neurofibroma
Neurofibromatosis 1
Neurofibromatoses

Pathways

Cell Proliferation
Localization
Cell Cycle
Pathogenesis
Hair Follicle Development
Primary Follicle Stage
Autocrine Signaling
Translation
Cell Differentiation
Eye Development
Epithelial Cell Proliferation
Enucleation
Cell Development

Response To Hypoxia
Odontogenesis
Response To Interferon-gamma
Senescence
Regeneration
Germ Cell Development
Organ Development

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTCH2

References

PMID: 9811851 by Carpenter D., et al. Characterization of two patched receptors for the vertebrate hedgehog protein family.

PMID: 9931336 by Smyth I., et al. Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene in basal cell carcinoma and medulloblastoma on chromosome 1p32.