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PTCHD4 Antibodies

AND PTCHD4 ELISA kits, PTCHD4 Proteins

Many biological assays use antibodies to detect PTCHD4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTCHD4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTCHD4 antibodies...

We validate the specificity of these antibodies to PTCHD4 by testing them on tissues known to express PTCHD4 positively and negatively. Browse below to find the PTCHD4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTCHD4 Infographic by Boster Bio

PTCHD4 protein infographic

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PTCHD4 Overview

Facts about Patched domain-containing protein 4.

PTCHD4 3D structure

PTCHD4 3D structure. Source: alphafold

Patched domain-containing protein 4 (PTCHD4)

Could function as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down- regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4-expressing cells. .

Gene Information

Human
Gene Name:	PTCHD4
Uniprot:	Q6ZW05
Entrez:	442213

Gene Information

Family

Belongs to:

patched family

Family

Alternative Names

Patched domain-containing protein 4

Molecular Weight

Mass (kDA):
96.371 kDA

Molecular Weight

Genomic Context


Human

Location:	6p12.3
Sequence:	6; NC_000006.12 (47858598..48111132, complement)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Subcellular Localization

PTMs

Glycoprotein

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For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTCHD4

References

PMID: 25296753 by Chung J.H., et al. A PTCH1 homolog transcriptionally activated by p53 suppresses hedgehog signaling.