Phosphatidylserine synthase 1 (PTDSS1)

Catalyzes a base-exchange reaction where the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine.

Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. .