Ptgdrl Antibodies

AND Ptgdrl ELISA kits, Ptgdrl Proteins

Many biological assays use antibodies to detect Ptgdrl, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ptgdrl in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ptgdrl antibodies...

We validate the specificity of these antibodies to Ptgdrl by testing them on tissues known to express Ptgdrl positively and negatively. Browse below to find the Ptgdrl antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ptgdrl Infographic by Boster Bio

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Ptgdrl Overview

Facts about Prostaglandin D2 receptor-like.

Ptgdrl 3D structure. Source: alphafold

Prostaglandin D2 receptor-like (Ptgdrl)

Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.

A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). .

Gene Information

Rat
Gene Name:	Ptgdrl
Uniprot:	O35932
Entrez:	498475

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

Prostaglandin D2 receptor-like

Molecular Weight

Mass (kDA):
39.803 kDA

Genomic Context


Rat

Location:	15p14
Sequence:	15;

Tissue Specificity

Strongly expressed in eye and gastrointestinal tract (GIT), moderately in the brain and oviduct and weakly in the epididymis. In the eye, expressed in the epithelium of the iris and ciliary body and in photoreceptor cells of the retina. In the brain, expressed in leptomeninges, choroid plexus and spinal cord (sensory and motor neurons of the dorsal and ventral horns). In the stomach, expressed in the mucous-secreting goblet cells and the columnar epithelium. Expressed in platelets.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ptgdrl

References

PMID: 9721719 by Gerashchenko D., et al. Dominant expression of rat prostanoid DP receptor mRNA in leptomeninges, inner segments of photoreceptor cells, iris epithelium, and ciliary processes.

PMID: 6302737 by Town M.H., et al. Pharmacological and cardiovascular properties of a hydantoin derivative, BW 245 C, with high affinity and selectivity for PGD2 receptors.