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PTP4A2 Antibodies
AND PTP4A2 ELISA kits, PTP4A2 Proteins
Many biological assays use antibodies to detect PTP4A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTP4A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTP4A2 antibodies...
Designing a Western blot for PTP4A2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PTP4A2 Western Blot GuideDesigning an IHC experiment for PTP4A2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PTP4A2 IHC GuidePTP4A2 Infographic by Boster Bio
All PTP4A2 Products
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PTP4A2 Overview
Facts about Protein tyrosine phosphatase type IVA 2.
Protein tyrosine phosphatase type IVA 2 (PTP4A2)
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors.
Inhibits geranylgeranyl transferase type II action by blocking the association between RABGGTA and RABGGTB. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PTP4A2 |
| Uniprot: | Q12974 |
| Entrez: | 8073 |
Family
| Belongs to: |
|---|
| protein-tyrosine phosphatase family |
Alternative Names
EC 3.1.3.48; HH13; HH7-2; HU-PP-1; HU-PP-1HH13; OV-1; OV-1PTP4A; PRL2; PRL-2; PRL-2HH7-2; PRL2protein tyrosine phosphatase IVA; protein tyrosine phosphatase IVA2; protein tyrosine phosphatase type IVA 2; protein tyrosine phosphatase type IVA, member 2; Protein-tyrosine phosphatase 4a2; Protein-tyrosine phosphatase of regenerating liver 2; PTP(CAAXII); PTP4A2; PTPCAAX2; PTPCAAX2phosphatase of regenerating liver 2; ptp-IV1a; ptp-IV1b
Molecular Weight
Mass (kDA):
19.127 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p35.2 |
| Sequence: | 1; NC_000001.11 (31906421..31938368, complement) |
Tissue Specificity
Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
Subcellular Localizations
Cell membrane. Early endosome. Cytoplasm.
Diseases
- Neoplasm Metastasis
- Neoplasms
- Malignant Neoplasms
- Cell Invasion
- Posttransfusion Purpura
- Neoplasm Invasiveness
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Colonic Neoplasms
- Colorectal Cancer
- Cell Transformation, Neoplastic
Pathways
- Prenylation
- Cell Proliferation
- Localization
- Cell Migration
- Cell Adhesion
- Pathogenesis
- Histone Modification
- Cell Division
- Cellular Localization
- Cell Motility
PTMs
- Prenylation
- Farnesylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTP4A2
bosterbio.com/bosterbio-gene-info-cards/PTP4A2
References
PMID: 8529999 by Montagna M., et al. A 100-kb physical and transcriptional map around the EDH17B2 gene: identification of three novel genes and a pseudogene of a human homologue of the rat PRL-1 tyrosine phosphatase.
PMID: 9018080 by Cates C.A., et al. Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases.