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- Table of Contents
Facts about Serine/threonine-protein phosphatase 2A activator.
Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly arouses the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro).
Human | |
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Gene Name: | PTPA |
Uniprot: | Q15257 |
Entrez: | 5524 |
Belongs to: |
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PTPA-type PPIase family |
Serine/threonine-protein phosphatase 2A activator
Mass (kDA):
40.668 kDA
Human | |
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Location: | 9q34.11 |
Sequence: | 9; NC_000009.12 (129110949..129148946) |
Widely expressed.
Cytoplasm. Nucleus.
PMID: 8195217 by Cayla X., et al. Molecular cloning, expression, and characterization of PTPA, a protein that activates the tyrosyl phosphatase activity of protein phosphatase 2A.
PMID: 8530035 by Van Hoof C., et al. Structure and chromosomal localization of the human gene of the phosphotyrosyl phosphatase activator (PTPA) of protein phosphatase 2A.