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- Table of Contents
PTPRE Antibodies
AND PTPRE ELISA kits, PTPRE Proteins
Many biological assays use antibodies to detect PTPRE, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPRE in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPRE antibodies...
Designing an IHC experiment for PTPRE? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PTPRE IHC GuidePTPRE Infographic by Boster Bio
All PTPRE Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05574-1
100 μg/vial
Cat # A05574-1
100 μg/vial
PTPRE Overview
Facts about Receptor-type tyrosine-protein phosphatase epsilon.
Receptor-type tyrosine-protein phosphatase epsilon (PTPRE)
Isoform 1 plays a vital role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PTPRE |
| Uniprot: | P23469 |
| Entrez: | 5791 |
Family
| Belongs to: |
|---|
| protein-tyrosine phosphatase family |
Alternative Names
DKFZp313F1310; EC 3.1.3.48; FLJ57799; FLJ58245; HPTPE; protein tyrosine phosphatase epsilon; protein tyrosine phosphatase, receptor type, E; protein tyrosine phosphatase, receptor type, epsilon polypeptide; Protein-tyrosine phosphatase epsilon; PTPE; receptor-type tyrosine-protein phosphatase epsilon; R-PTP-EPSILON
Molecular Weight
Mass (kDA):
80.642 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q26.2 |
| Sequence: | 10; NC_000010.11 (127907053..128085855) |
Tissue Specificity
Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells).
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm. Predominantly cytoplasmic. A small fraction is also associated with nucleus and membrane. Insulin induces translocation to the membrane (By similarity).; [Isoform 3]: Cytoplasm.
Diseases
- Posttransfusion Purpura
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Mammary Neoplasms
- Nervousness
- Tissue Adhesions
- Leukemia
- Carcinoma
- Pathologic Neovascularization
- Mammary Neoplasms, Experimental
- Allergic Asthma
Pathways
- Localization
- Cell Growth
- Transport
- Myelination
- Cell Differentiation
- Cell Proliferation
- Cytokine Production
- Rna Processing
- Secretion
- Osteoclast Differentiation
- Hyperphosphorylation
- Immune Response
- Endothelial Cell Proliferation
PTMs
- Phosphorylation
- Dephosphorylation
Research Areas
- GPCR
- Protein Phosphatase
- Tyrosine Kinases
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPRE
bosterbio.com/bosterbio-gene-info-cards/PTPRE
References
PMID: 2170109 by Krueger N.X., et al. Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.
PMID: 12121439 by Wabakken T.K., et al. Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase.