PYGB Antibodies

AND PYGB ELISA kits, PYGB Proteins

Many biological assays use antibodies to detect PYGB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PYGB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PYGB antibodies...

We validate the specificity of these antibodies to PYGB by testing them on tissues known to express PYGB positively and negatively. Browse below to find the PYGB antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PYGB Infographic by Boster Bio

All PYGB Products

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Specificity

Applications

Price

GPBB (PYGB) (NM_002862) Human Over-expression Lysate

Human

$628
Cat # LS005834
20 µg, 100 µg

Anti-PYGB Antibody Picoband®

Western blot analysis of PYGB using anti-PYGB antibody (A08012-1)

IHC analysis of PYGB using anti-PYGB antibody (A08012-1)

Human, Rat

IHC, WB

$370
Cat # A08012-1
100 μg/vial

PYGB Overview

Facts about Glycogen phosphorylase, brain form.

PYGB 3D structure. Source: alphafold

Glycogen phosphorylase, brain form (PYGB)

Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852). Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).

Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228). However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).

Gene Information

Human
Gene Name:	PYGB
Uniprot:	P11216
Entrez:	5834

Family

Belongs to:

glycogen phosphorylase family

Alternative Names

Brain glycogen phosphorylase; EC 2.4.1.1; Glycogen phosphorylase B; Glycogen phosphorylase brain form; Glycogen Phosphorylase Isoenzyme BB; GPBB; MGC9213; Phosphorylase glycogen brain; PYGB

Molecular Weight

Mass (kDA):
96.696 kDA

Genomic Context


Human

Location:	20p11.21
Sequence:	20; NC_000020.11 (25248039..25298012)

Diseases

Reperfusion Injury
Malignant Neoplasm Of Breast
Occlusion, Middle Cerebral Artery
Trauma, Nervous System
Insulin Resistance
Malignant Neoplasms
Neoplasms
Nervousness
Cerebrovascular Accident
Innate Immune Response
Infarction, Middle Cerebral Artery
Mammary Neoplasms

Cerebral Artery Occlusion
Cerebral Ischemia
Hereditary Diseases
Ischemia
Kidney Failure, Chronic
Tissue Adhesions

Interacting Proteins

PYGL
SIAH1

Pathways

Localization
Transport
Cell Adhesion
Cell Death
Limb Morphogenesis
Innate Immune Response
Ion Transport
Immune Response

Cell Growth
Metaphase
Segmentation

PTMs

Acetylation

Phosphoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PYGB

References

PMID: 3346228 by Newgard C.B., et al. Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes.

PMID: 2615594 by Gelinas R.P., et al. Human brain glycogen phosphorylase: characterization of fetal cDNA and genomic sequences.