PYGL Antibodies

AND PYGL ELISA kits, PYGL Proteins

Many biological assays use antibodies to detect PYGL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PYGL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PYGL antibodies...

We validate the specificity of these antibodies to PYGL by testing them on tissues known to express PYGL positively and negatively. Browse below to find the PYGL antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PYGL? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PYGL Western Blot Guide

PYGL Infographic by Boster Bio

All PYGL Products

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Product

Figures

Specificity

Applications

Price

Anti-PYGL Antibody Picoband®

Western blot analysis of PYGL using anti-PYGL antibody (A06317-1)

IHC analysis of PYGL using anti-PYGL antibody (A06317-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06317-1
100 µg/vial

Anti-PYGL Antibody (C-Term)

M06317 staining PYGL in human liver tissue sections by Immunohistochemistry (IHC-P -paraformaldehyde-fixed, paraffin-embedded sections)

Human, Mouse

IHC-P, WB

$299
Cat # M06317
50 µl

PYGL (NM_002863) Human Over-expression Lysate

Human

$628
Cat # LS005836
20 µg, 100 µg

Human PYGL Recombinant Protein

SDS-PAGE

$268
Cat # PROTP06737
Starting from 10ug

PYGL Overview

Facts about Glycogen phosphorylase, liver form.

PYGL 3D structure. Source: alphafold

Glycogen phosphorylase, liver form (PYGL)

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.

However, all known phosphorylases share catalytic and structural properties. .

Gene Information

Human
Gene Name:	PYGL
Uniprot:	P06737
Entrez:	5836

Family

Belongs to:

glycogen phosphorylase family

Alternative Names

EC 2.4.1.1; glycogen phosphorylase, liver form; GSD6; phosphorylase, glycogen, liver; phosphorylase, glycogen; liver

Molecular Weight

Mass (kDA):
97.149 kDA

Genomic Context


Human

Location:	14q22.1
Sequence:	14; NC_000014.9 (50905217..50944483, complement)

Diseases

Glycogen Storage Disease
Glycogen Storage Disease Type Vi
Hypoglycemia
Hepatomegaly
Storage Disease
Malignant Neoplasms
Neoplasms
Glycogen Storage Disease Type V
Cholangiocarcinoma
Diabetic Ketoacidosis
Mutation, Out-of-frame
Hypoxia
Glycogen Storage Disease Type Iv

Neoplasm, Residual
Fasting Hypoglycemia
Recurrent Severe Hypoglycemia
L1 Acute Lymphoblastic Leukemia
Neuroblastoma
Cell Transformation, Neoplastic
Hereditary Diseases

Interacting Proteins

PYGB

Pathways

Localization
Transport
Stem Cell Differentiation
Response To Hypoxia
Metaphase
Neuron Differentiation
Oocyte Maturation
Oxidative Phosphorylation
Biosynthetic Process
Glucose Homeostasis
Senescence

Translation
Cell Cycle
Cell Differentiation
Cell Growth
Steroid Biosynthetic Process

PTMs

Acetylation

Phosphoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PYGL

References

PMID: 2877458 by Newgard C.B., et al. Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage.

PMID: 9536091 by Chang S., et al. Identification of a mutation in liver glycogen phosphorylase in glycogen storage disease type VI.